scirrhous carcinoma

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Related to scirrhous: scirrhous carcinoma, scirrhous cord

scirrhous carcinoma

[′sir·əs ‚kärs·ən′ō·mə]
(medicine)
A hard, poorly differentiated adenocarcinoma in which the anaplastic cells are surrounded by dense bundles of collagenous fibers.
References in periodicals archive ?
CK7 staining is strongly and diffusely positive in FLC, scirrhous HCC, and intrahepatic cholangiocarcioma.
Surgical management of scirrhous cord in ongole bullocks - A report of two cases.
(5) The differential diagnosis of silent sinus syndrome includes atrophy of the orbital contents secondary to Wegener granulomatosis, scirrhous metastasis, chronic sinusitis, and osteomyelitis, among others.
The internal medicine is effective in terminal cancer cases including prostate carcinoma, gastric cancer, scirrhous gastric cancer, sigmoid colon cancer, uterine cancer, esophageal cancer, colon cancer, pancreatic cancer, and lung cancer, and also has produced complete remission of malignant lymphoma and leukemia.
However, similar thickening may also be seen in Menetrier's disease, lymphoma, scirrhous carcinoma, Crohn's disease, and granulomatous disease.
Also, tumors with extensive fibrosis like scirrhous carcinoma can give a false negative result because of low cellularity which can be avoided by performing FNAC in the periphery of the tumor with 27-gauge needle in this type of malignancies [9].
Signet-ring cell carcinomas account for up to 15% of all gastric cancers and typically cause scirrhous infiltration of the gastric wall (linitis plastica).
Frequent amplification of the c-met gene in scirrhous type stomach cancer.
Adenocarcinomas of the stomach, lung, colon, pancreas and breast, in addition to lymphoma, sarcoma and carcinoids, have been repeatedly mentioned as causes of MRPF.[sup.1] The incidence of ureteral involvement in neoplasia is 0.2%.[sup.2] The phenomenon of MRPF is due to the ability of scirrhous tumours, such as adenocarcinomas, to produce an extracellular desmoplastic reaction.[sup.3] The increase in soft tissue density around the ureters on CT, the ureteral appearance on retrograde pyelography and the desmoplastic reaction seen on the histologic sections taken from the peritoneal implants suggest that distal bilateral ureteral obstruction in our patient was the result of MRFP.
This is most like to occur in metastatic scirrhous and solid prostate cancer with regional lymphadenopathy and with severe changed fibrotic stroma [10].