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a skin condition characterized by a secretory disorder of the sebaceous glands. Seborrhea occurs in both sexes, usually during puberty, and is undoubtedly associated with neuroendocrine disorders. It affects the scalp, face, chest, and back.

Several forms of seborrhea are distinguished: seborrhea adiposa, concrete seborrhea, and mixed seborrhea. During seborrhea adiposa, sebum is secreted in abnormal amounts and accumulates on the skin; the ducts of the sebaceous glands are enlarged and gaping. Hair on the head is greasy and shiny and falls out readily, causing thinning hair in women and permanent baldness in men. Other symptoms include an increase in nervous excitability, fluctuations in arterial pressure, and other functional disorders of the autonomic nervous system. The intensity of sebum secretion decreases by the age of 24–26 years.

Concrete seborrhea is characterized by a less abundant secretion of sebum. An increased keratinization of the openings of the hair follicles obstructs the ducts of the sebaceous glands and results in the formation of blackheads, or comedones. The skin hardens at the affected sites, is dirty gray in appearance, and tends to form blackheads, keratin cysts, and scars; desquamation is pronounced and endocrine disorders are common. Hair does not usually fall out, and the process abates by the age of 26–28 years.

During mixed seborrhea, the symptoms of seborrhea adiposa are prominent on the face and scalp, and the symptoms of concrete seborrhea are prominent on the back and chest.

The treatment of seborrhea is directed at normalizing the activity of the endocrine glands (hormone therapy) and the nervous system (bromine and bismuth preparations, vitamins B1 and B6, hydrotherapy) and stimulating metabolic processes, for example, by the administration of blood transfusions, multiple vitamins, or arsenicals. External treatments include the application of paraffin and skin disinfectants (2 percent salicyl alcohol or resorcinol), the use of ultraviolet irradiation, and the removal of comedones.


Korolev, Iu. F. Seboreia. Leningrad, 1963.


References in periodicals archive ?
In our current study, 6 cases were diagnosed as basal cell carcinoma on RCM; however, biopsy showed angiofibroma in 4 cases, sebaceous gland hyperplasia in 1 case, and inflamed seborrheic keratosis in 1 case.
The most common mucocutaneous lesions were observed viral infections in 90 (53.0%) patients, bacterial infections in 82 (48.2%) patients, fungal infections in 63 (37.0%) patients, hair changes in 51 (30.0%) patients, seborrheic dermatitis in 51 (30.0%) patients, parasitic infestation in 49 (28.8%) patients, oral candidiasis in 28 (16.5%) patients, drug reactions and hair changes in 17 (10.0%) patients, papulosquamous disorders 14 (8.2%) patients.
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Seborrheic means "greasy" and keratosis means "thickening of the skin." Despite the name, SKs are not known to be caused by an abundance of sebum in the skin, nor are they limited to areas of increased oil production.
The FDA approval for the product is based on two pivotal Phase three trials that demonstrated the safety and efficacy of Eskata for the treatment of raised seborrheic keratosis.
We adopted the Seborrheic Dermatitis Area Severity Index (SDASI) scoring system.[sup][13] In brief, the erythema and desquamation of nine different anatomic sites were graded from 0 to 3 (0 = none, 1 = mild, 2 = moderate, and 3 = severe).
Kamedis says the system, comprising a scalp lotion and a dandruff shampoo, offers the first therapeutic two-step process to fight dandruff and seborrheic dermatitis.
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Malassezia genus are the yeast that cause systemic disease like fungemia and are involved in other diseases such as dandruff , seborrheic dermatitis, onychomycosis, psoriasis, sinusitis, peritonitis, fungemia, blepharitis, folliculitis and inflammation of the lacrimal duct.
The breakthrough study identified multiple potential targets for treating diseases such as seborrheic dermatitis, eczema and dandruff, all of which can be caused by Malassezia.
Malvern, Pennsylvania-based Aclaris is working on what looks set to become the first topically applied therapy for removing common skin tumour seborrheic keratosis (SK) and other verrucoid lesions of the skin.