Besson, "Promoting effect of water for aliphatic primary and secondary alcohol
oxidation over platinum catalysts in dioxane/aqueous solution media," Catalysis Today, vol.
The absolute configuration of the C-15 secondary alcohol
in 1 was deduced via the CD data of the in situ formed [[Rh.sub.2][(OCOC[F.sub.3]).sub.4]] complex with acetonide 1a (Figure 3).
is the reduction in activation energy the same for reactions with secondary alcohols
as with primary alcohols).
If a preponderance of ethanol in the resources has selected a higher ADH activity, we could expect this increase to result from a modification of the active site of the enzyme, favoring TABULAR DATA OMITTED a better affinity of the enzyme for a primary alcohol (such as ethanol) relatively to a secondary alcohol
. To check this hypothesis, the following ratio (E/I) was calculated:
In fermenting fruit, for instance, ethanol is found up to 5% (v/v; 868 mM), whereas propan-2-ol, a saturated secondary alcohol
, does not reach levels above 0.1% (13 mM) (McKechnie and Morgan 1982).
An efficient reagent for oxidation of primary and secondary alcohols
to carbonyl compounds.
can also be transformed to ketones almost as quickly as the benzyl alcohol (entry 4, Table 2) with TEMPO catalysis.
In continuation of our efforts on the use of different mixed metal oxide nanoparticles as an efficient catalyst for the selective oxidation of alcohols in presence of molecular [O.sub.2] [18, 32, 41, 48, 49], we demonstrate herein a facile and straightforward procedure for the preparation of Zn[O.sub.x] NPs doped manganese carbonates or oxides employed for oxidation of secondary alcohols
with environmentally friendly oxidizing agent such molecular [O.sub.2] which produces water as the only by-product under base-free conditions.