* When a reagent has a secondary amine
structure (e.g., diethanolamine or its derivatives are used as linkers in many synthetic process), it would be prudent to look for nitrosamines related to these amines.
Saga et al., "Ultra-sensitive HPLC-photochemical reaction-luminol chemiluminescence method for the measurement of secondary amines
after nitrosation," Analytica Chimica Acta, vol.
Aliphatic amines quench the fluorescence intensity of aromatic hydrocarbons and themselves do not fluoresce, hence intrinsic fluorescence characterization is inapplicable for epoxy prepolymers cured with aliphatic amines , Mid-FTIR (600-4000 [cm.sup.-1]) characterization has been used to measure epoxy functional group reaction kinetics; however, the methods are not capable of providing clear distinction between epoxy, primary, and secondary amine
concentration changes due to band overlap.
Curing of epoxide groups with amine hardeners revealed that the primary amine hydrogen reacts with the epoxy resin and subsequently the secondary amine
hydrogen comes into exist which can react with the other epoxy ring.
Both DMMXDA and p-NMAz are difunctional secondary amines
, and hence incapable of crosslinking.
The compound is obtained by reacting at least one hydroxyalkyl ester of an olefinically unsaturated carboxylic acid with two to 12 carbon atoms in the hydroxyalkyl residue with at least one lactone and with at least one hydroxy-functional amine having two to 10 carbon atoms per molecule and where the amino group is selected from the group consisting of primary amines, secondary amines
and mixtures thereof and the hydroxy-functional amine is selected from the group consisting of hydroxy functional alkyl amines, hydroxy-functional cyclo alkylamines, hydroxy-functional alkoxyamines and any mixtures thereof; at least one cross-linking agent with functional groups reactive towards active hydrogen and optionally, at least one binder with functional groups containing active hydrogen.
(nortriptyline and desipramine) tend to produce fewer of these effects than do the tertiary amines (amitriptyline, imipramine).
Bauer prefers the secondary amines
nortriptyline or desipramine, or doxepin or imipramine for patients who need help sleeping.
Although reaction of alkyl halides with ammonia or primary amines can result in the formation of quaternary salts, in the presence of a large excess of amine, the reaction can yield primary and secondary amines
. The polymeric species will be less reactive towards the amine as is the case of PVC.
(9) found that methylbenzylnitrosamine, nitrososarcosine ethyl ester, and other secondary amines
induced carcinoma of the esophagus in rats.
This includes primary and secondary amines
, amino acids, protein hydrolysates, active methylene esters, thiols, bisulfites and conditions of alkaline pH.
The study of the absorption and release of C[O.sub.2] by the use of secondary amines
(with N-alkylcarbamate formation) is currently in progress.