Failure to differentiate PSH from seizure activity may result in ineffective treatment and secondary complications from increased intracranial pressure, dehydration, cardiac dysrhythmias, and secondary brain injury
from prolonged sympathetic response, which are associated with longer hospitalizations, increased morbidity, and increased mortality (Farias-Moeller et al., 2015; Kirk et al., 2012; Rabinstein & Benarroch, 2008; Raithel et al., 2015).
Intensive care unit nurse characteristics impacting judgments about secondary brain injury
. Dimens Crit Care Nurs.
Promising strategies to minimize secondary brain injury
after brain trauma.
Neuroinflammation plays a key role in secondary brain injury
after ICH and is associated with both brain damage and recovery from ICH .
Strategies to minimize secondary brain injury
are important for the initial management of an impalement brain injury.
Zha, "Genetic ablation of toll-like receptor 2 reduces secondary brain injury
caused by cortical contusion in mice," Annals of Clinical and Laboratory Science, vol.
Early treatment with desmopressin may reduce hypernatremia and perhaps secondary brain injury
The breakdown of the BBB can result in brain edema and increase in intracranial pressure (ICP), accompanied by activation of secondary brain injury
by impairing cerebral perfusion and oxygenation .
Therefore, potential therapeutic strategies targeting secondary brain injury
are attracting a lot of attention in translational studies of hemorrhagic stroke.
Recently, the researchers have targeted the secondary brain injury
due to the primary brain injury.
This phenomenon may cause secondary brain injury
and further compromise the patients' recovery.
Numerous preclinical studies show that secondary brain injury
after ICH is caused by the interaction of cytotoxicity, excitotoxicity, oxidative stress (OS), and inflammation from the products of red blood cell lysis and plasma components [3, 4].