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In some micrographs, large secondary lysosomes enclosing partly decomposed collagen fibrils were observed (Fig.
The collagen-containing secondary lysosomes observed in some of these cells suggest they may have a fibroclastic function, cleaning up the connective tissue compartment before new collagen synthesis starts.
Columnar epithelial cells had a prominent, basally located pleomorphic nucleus and exceptionally large and abundant secondary lysosomes (Figs.

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