For comparison, secretory granules
have diameters on the order 100-500 nm [16-19].
Rapid ATP-dependent priming of secretory granules
precedes [Ca.sup.2+]-induced exocytosis in mouse pancreatic B-cells.
Hoops, "The pancreatic membrane protein GP-2 localizes specifically to secretory granules
and is shed into the pancreatic juice as a protein aggregate," European Journal of Cell Biology, vol.
Proteoglycan 1, secretory granule
(PRG1), an early response gene regulated by P53 and NF-[kappa]B (Schafer et al.
Electron density of the secretory granule
was low, and the internal space of the secretory granule
was filled with fine granular substances.
Many secretory granules
ultra structurally visible were electron-dense, uniformly spherical and generally 240 to 410 nm in diameter, with no gap between membrana limitans and endocrine (Fig.
Also, the epididymis showed some regression signals, in particular, the epithelial cells lining the corpus were poorly secreting, and very few spermatozoa and secretory granules
were present in the lumen (Figure 2(c)).
Neutrophils secrete their products via a variety of the mechanisms, including fusion of secretory granules
with the plasma membrane  and shedding of membrane vesicles (ectosomes) from the plasma membrane [35-39].
The centroacinar cells were located in the gland cavity which was surrounded by the gland cells that were lighter in color, contained a kernel that was not obvious, and there were no secretory granules
in the cytoplasm (Fig.
H&E images of the cGVHD-impaired murine lacrimal gland showed inflammatory cell infiltration into the stroma and decreased secretory granules
in the epithelia (Figures 2(a), 2(b), 2(c), and 2(d)).
Specific (secondary) granules include proteins such as lactoferrin and lysozyme, and gelatinase (tertiary) granules contain leukolysin and matrix metalloproteinase 9 (MMP9; also known as gelatinase B) and finally quaternary (secretory granules