Are cavum septum pellucidum
abnormalities more common in schizophrenia spectrum disorders?
The septum pellucidum is a single leaflet formed embryologically by fusion of two laminae and serves to separate the lateral ventricles.
We present a case of a 30 year old Caucasian female with an absent septum pellucidum and gray matter heteropia who was diagnosed with schizoaffective disorder.
The neurosurgeon recommended two treatment options: surgical resection of the colloid cyst or ventriculoperitoneal shunting with fenestration of the septum pellucidum
via a scope.
Sonographic analysis of the midline will reveal the distinctive corpus callosum in the coronal scan plane as a hypoechoic bridge of tissue superior to the cavum septum pellucidum
. (See Fig.
PATIENT'S MRI: Note agenesis of corpus callosum and absence of septum pellucidum
(see page 95).
Patient's MRI showed cortical and subcortical atrophy, enlarged ventricles, and cavum septum pellucidum
CT to Predict Site or Ruptured Aneurysm: Considering distribution of subarachnoid hemorrhage in early CT taken within 24hours, based on previous studies, presence of subarachnoid hemorrhage in anterior interhemispheric fissure and/or septum pellucidum
and/or pericallosal sulci is assumed to be due to Acom/ACA aneurysm rupture.
At this point, the plan was made to take her to the operating room the following day to remove the mass and possibly fenestrate the septum pellucidum
. However, the following morning, her mental status deteriorated abruptly to the point that she became obtunded.
The tumor is thought to be derived from the granular neurons of the small gray nuclei of the septum pellucidum
and fornix, or from remnants of the subependymal plate of the lateral ventricles.
Associated anomalies were absent septum pellucidum
Age, y/Sex/Race Site 1 20/F/W Left frontal lobe 2 36/M/B Thoracic spinal cord 3 42/F/W Third ventricle 4 24/F/W Pontocerebellar angle 5 39/M/B Leftfrontal lobe 6 29/F/W Septum pellucidum
7 35/M/B Right basal ganglia 8 29/F/A Left cerebrum 9 39/M/W Left frontal lobe 10 78/M/B Pituitary/frontal lobes 11 45/M/W Right frontal lobe 12 49/M/W Brainstem/basal ganglia 13 46/M/W Parietal/brainstem 14 61/M/W Bilateral 15 43/M/W Basal ganglia 16 46/F/W CP angle/spinal cord 17 43/F/B Right cerebrum 18 36/M/B Right temporal lobe 19([dagger]) 47/F/B Left frontal/basal ganglia 47/F/B Left frontal lobe 20 44/F/W Medulla 21 74/F/B Pituitary stalk 22 43/F/B Right fronto-orbital 23 7/M/W Right CP angle 24 15/F/W Corpus callosum 25 .../F/...