Sequestrum


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Related to Sequestrum: involucrum

sequestrum

[si′kwes·trəm]
(medicine)
A piece of dead or detached bone within a cavity, abscess, or wound.

Sequestrum

 

a piece of tissue that has died as a result of a circulatory disorder and become separated from the surrounding healthy tissue. A sequestrum may develop, for example, during osteomyelitis. Sequestration may also occur in lung, tendon, or muscle tissue. While in the body, a sequestrum continuously promotes the suppurative process. A sequestrum may be discharged from the body with the flow of pus; sometimes, however, it is necessary to remove it surgically

References in periodicals archive ?
In the process of surgical exploration and debridement, necrotic tissues on the wound surface were completely removed, including sequestrum and cicatricial tissue with poor blood supply; the original internal fixation device was removed and replaced with external fixation or gypsum back slab; reduction was performed at the bone defect site as best as possible, with internal fixation and realignment of fracture The antibiotic-loaded bone cement spacer was planted at the gap and if the wound was large or had poor soft tissue coverage, vacuum sealing drainage was used to assist the attachment with negative pressure.
aureus + Ceftriaxone group was characterized by the presence of severe and acute suppurative inflammation plus bone sequestrum (acute suppurative osteomyelitis) extending to the fracture site and the periosteal surface.
The tympanic part of the temporal bone was drilled out, and a large sequestrum was removed (Figure 3(c)).
In the advanced stages, osteosclerosis, irregular bone surface, and the separation of sequestrum are observed [7].
Las tesiones titicas en huesos pueden contener un centro de materiat oseo intacto conocido como "boton de secuestro"(button sequestrum).
Physical and ophthalmic examination like schirmer tear test, fluorescein dye test and slit lamp biomicroscopy revealed chronic keratitis and corneal sequestrum. Partial keratectomy followed by pedicle bulbar conjunctival graft was undertaken and the animal recovered uneventfully after surgery with no recurrence.
The bullet was removed, the abscess drained, the bony sequestrum removed and the bone curetted during surgery.
Radiographic imaging findings associated with Ficat-Arlet stages of osteonecrosis of the hip Stage Radiographic Findings 0 Preclinical Normal or near-normal I Preradiographic Normal or near-normal II Prior to head collapse * Trabecular pattern changes or sequestrum * Sclerosis, decalcification, formation or a mix of both III Collapse * Crescent sign and broken contour of the femoral head * Sequestrum * Normal or increased joint space due to collapse IV Degenerative * Flattened contour of femoral head * Decreased joint space * Acetabular osteophytes
Surgical debridement and removal of sequestrum, if present is essential before starting antibiotic and antifungal therapy.
A sequestrum or involucrum will only be seen in 10% of cases.
The antibiotics are unable to penetrate these floating islands of infected bone to eradicate the infection.9 The definitive treatment of chronic osteo- myelitis with diabetes depends on adequate surgical debridement and removal of sequestrum. Patients with chronic osteomyelitis may develop local suppurative complications such as surrounding cellulitis or sys- temic complications such as bacteremia.10