serine protease


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serine protease

[¦se‚rēn ′prōd·ə‚ās]
(cell and molecular biology)
A family of endopeptidases whose proteolytic activity involves the hydroxy group of the serine residue; they play an important role in digestion, blood clotting, and the complement system.
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References in periodicals archive ?
coli (EHEC)-secreted serine protease EspP stimulates electrogenic ion transport in human colonoid monolayers.
It is a member of the serine protease family and is secreted in Otsuka Long-Evans Tokushima Fatty (OLETF) rats in case of obesity and peak insulin plasma concentrations from the visceral adipose tissue.16 Vaspin is considered a novel biomarker that is potentially effective against obesity and impaired insulin tolerance, and it is released as an antiprotease factor in visceral adipose tissue; clinically worsening diabetes and weight loss decrease vaspin expression.
High temperature requirement factor A1 (HtrA1), a member of the HtrA family of proteins, consists of a trypsin-like serine protease domain, a PDZ domain, an IGFBP/mac25-like domain, and a kazal-type inhibitor domain (5).
(2010) have found that the optimum pH is from 7-11 for the production of serine protease by Aspergillus terreus.
Studies have highlighted NS2B-NS3, a serine protease, as a key player in ZIKV replication (Mackenzie, 2005; Li et al., 2017).
Trypsin activity was inhibited by 63% for females and 75% for males, using TLCK as an inhibitor; the serine protease activity was inhibited by 91% for females and 87% for males using PMSF, and 85% for females and
Boric acid (the form in which boron occurs in nature) is a serine protease inhibitor, and serine protease inhibitors have been found to inactivate the E7 oncoprotein expressed by high- risk HPV strains (HPV- 16 and HPV-18).
Anti-plasma serine protease inhibitor (SERPINA5), hepatocyte growth factor activator (HGFAC), anti-leucine zipper protein 4 (LUZP4), and anti-phosphoinositide phospholipase C (PLCH2) were used (Abcam, USA).
Reumers et al., "Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease," Human Mutation, vol.
The C1-inhibitor, C1-INH, is the only known serine protease plasma inhibitor.
In this study, a serine protease (Spbtry1) gene was cloned from the soybean pod borer larvae midgut, and its transcription profiles in various developmental stages and tissues were determined.

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