When suspected, EUS aspiration will be performed before surgical excision to exclude other cystic lesions, including a pseudocyst and serous cystadenoma
The neoplasms characteristically associated with VHL disease include hemangioblastomas of the central nervous system and retina, angiomas of the retina, endolymphatic sac tumors, clear cell renal cell carcinomas (RCCs) and cysts, pancreatic serous cystadenomas
and neuroendocrine tumors, pheochromocytomas, cystadenomas of the epididymis and broad ligament, neuroendocrine tumors of the lungs, and various benign cysts and hemangiomas of the lungs, liver, spleen, adrenal glands, bones, and skin.
have been estimated to account for about 25% of all cystic tumors of the pancreas, but the true incidence is difficult to determine.
Editorial accompanies publication of CONTACT 1 Study results showing that needle-based confocal laser endomicroscopy with Cellvizio able to confirm benign serous cystadenomas
with 100% specificity.
In the series of Recine et al, (94) 2 of 19 tumors believed to represent mucus-producing cystic neoplasms on FNA proved to be serous cystadenoma
Oligocystic (Macrocystic) Variant of Serous Cystadenoma
A solid variant of serous cystadenoma
(solid serous adenoma) exists that has no cystic areas.
(SC), also known as microcystic adenoma or glycogen-rich cystadenoma, is a rare, usually benign pancreatic neoplasm that occurs most often in women and is typically diagnosed during the sixth to ninth decades of life.
Serous microcystic adenomas are benign tumors of the pancreas and are also known as glycogen-rich cystadenomas or serous cystadenoma
Those results show a strong sensitivity and specificity for the 3 categories of cysts (respectively 69% and 100% for serous cystadenomas
, 91% and 95% for mucinous cysts and 43% and 100% for pseudocysts).
3) Blood products, if present, aid in differentiating SPT from other pancreatic masses including pseudocysts, serous cystadenomas
, mucin-producing neoplasms and islet cell tumors.
While most serous cystadenomas
(SCAs) can be managed nonoperatively, patients with mucinous cystic neoplasms (MCNs), solid pseudopapillary tumors (SPTs), main-duct intraductal papillary mucinous neoplasms (IPMNs) should undergo surgical resection.