sialomucin


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Related to sialomucin: sulfomucin

sialomucin

[sī¦al·ə′myüs·ən]
(biochemistry)
An acid mucopolysaccharide containing sialic acid as the acid component.
References in periodicals archive ?
1993) Binding of L-selectin to the vascular sialomucin CD34.
2004) Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.
Potentiation of metastasis by cell surface sialomucin complex (rat MUC4), a multifunctional anti-adhesive glycoprotein.
Overexpression of sialomucin complex, a rat homologue of MUC4, inhibits tumor killing by lymphokine-activated killer cells.
In that also neutral are more and in acidic sialomucins are more than sulfomucins.
Since phenylhydrazine blocks specially the aldehyde produced by neutral glycoprotein, only the aldehyde formed by sialomucins and sulfomucins remain reactive to PAS (Pearse; Bancroft & Cook).
Glickman et al (8) evaluated multilayered epithelium in samples obtained from 17 patients and found that its glandular cells expressed neutral mucins, sialomucins, and sulfomucins at rates comparable to Barrett esophagus (88%, 100%, and 71% of cases, respectively, versus 100%, 100%, and 76%, respectively).
A variable proportion of cells have intracytoplasmic lumina containing demonstrable sialomucins with the mucicarmine and Alcian blue stains.
The study of the mucinous component of the neoplasm was performed using 2 stains: (1) the AB-PAS stain, which distinguishes between acid mucins stained blue by AB and neutral mucins stained magenta by PAS; and (2) the AB-HID stain, which differentiates sulfomucins stained brownish by HID and sialomucins stained blue by AB.