CHADS2 and CHA2DS2-VASc score to assess risk of stroke and death in patients paced for sick sinus syndrome
. Heart 2013;99:843-8.
New insights into pacemaker activity: promoting understanding of sick sinus syndrome
Sinus bradycardia (sinus rhythm of less than 60 bpm) can be normal in specific instances, but specific causes such as ischemic heart disease, sick sinus syndrome
, and noncardiac causes such as metabolic causes, medications, and toxins exist [1-4].
Lei, "Multiple loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome
," PLoS ONE, vol.
"When they told me I had Sick Sinus Syndrome
, I was still allowed to work as a firefighter," he said.
Prof Zhang said: "Previously, we did not know why some people with sick sinus syndrome
would die suddenly, but now we do know why risk can increase at night during sleep.
A Sick sinus syndrome
(SSS) is caused by improper function of the sinoatrial (sinus) node, known as the "heart's pacemaker." The condition manifests as a rapid heartbeat (tachycardia), slow heartbeat (bradycardia) or both.
Main indications for pacing were atrioventricular (AV) block, sick sinus syndrome
(SSS) and slow ventricular rate during atrial fibrillation in both periods.
He had gastroesophageal reflux, a funnel chest, lower limb fracture and sick sinus syndrome
as well as the characteristic developmental delay, neurological degeneration and growth retardation.
Sick sinus syndrome
(SSS) is a group of conditions that occur when the sinus node doesn't work as well as it should.
The SCN5A gene governs the behavior of cardiac sodium ion channels, and mutations in the gene are known to cause long QT syndrome, Brugada syndrome, sudden unexplained nocturnal death syndrome, ventricular fibrillation, congenital sick sinus syndrome
, and progressive cardiac conduction defect.