hemoglobin S

(redirected from sickle cell hemoglobin)
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hemoglobin S

[′hē·mə‚glō·bən ′es]
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ACS occurs in children with sickling hemoglobin (HbS) presenting as classic sickle cell hemoglobin (HbSS); however, ACS may also occur in Sickle-thalassemia, and Sickle-hemoglobin C disease (HbSC).
Each test requires 2 ml of reconstituted solubility buffer and 20 [micro]l of anticoagulated whole blood or 20 [micro]l of sickle cell hemoglobin control.
Sickle Cell Hemoglobin (HbAS) indicates as sickle cell trait and Sickle cell disease (HbSS) indicates as sickle cell anemia with hemoglobin electrophoresis.
Sickle cell hemoglobin occurs as a result of thymine replacing adenine in the sixth codon of the beta-globin gene.
Moskowitz, "Ever since Max Perutz showed the molecular defect in sickle cell hemoglobin in 1946, for which he won the Nobel Prize, sickle cell disease has been a sober reminder that knowing the molecular cause of a disease is still a far cry from curing it.
In 1949 Pauling and his associates showed that sickle cell hemoglobin (HbS) belonged to an abnormal molecular species.
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