side chain


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side chain

[′sīd ‚chān]
(organic chemistry)
A grouping of similar atoms (two or more, generally carbons, as in the ethyl radical, C2H5‒) that branches off from a straight-chain or cyclic (for example, benzene) molecule. Also known as branch; branched chain.
References in periodicals archive ?
This results in the disruption of G199(C=O)-A202(N-H) H-bond, subsequent transformation of PBC short helix from [3.sub.10] to [alpha]-form, and packing of the L203 side chain into the hydrophobic pocket formed by [beta]2[beta]3-loop.
The ratio of the peak area of C[F.sub.3] and C[F.sub.2] ([MATHEMATICAL EXPRESSION NOT REPRODUCIBLE IN ASCII]), estimated from the [C.sub.1s] spectrum of the air-side surface, was about 1/4.8 and is analogous to the 1/5 existence ratio of C[F.sub.3] and C[F.sub.2] groups calculated from the chemical composition of the perfluoroalkyl side chain. This means that the top surface of the modified alicyclic epoxy resin in this study is mainly composed of the fluorinated side chains which are oriented along the surface as mentioned in the previous section (Fig.
As observed among samples 2, 5, and 6, the [M.sub.c] decreased and the XLD increased as the side chain content of com-patibilizers increased.
At 4 [Angstrom], the backbone may appear connected, but side chains might not be very distinguishable.
Penicillin skin testing can accurately predict a penicillin-allergic reaction, but is not predictive for cephalosporin allergy unless the side chain of the penicillin or ampicillin testing reagent is similar to the cephalosporin side chain being evaluated.
"A rubber belt over heavy cross channels with a steel side chain is recommended for this application," he comments.
Now, however, we know that the [beta]-lactam ring of cephalosporins--unlike that of penicillin and ampicillin--becomes rapidly degraded, so that antibodies are instead targeted to side chain structures.
The interrelationships between structure, antimicrobial activity, and side effects associated with various side chain positions of the quinolones are discussed here.
Prior to the crystal structure determination, molecular modeling indicated that the [beta]Thr67 side chain hydroxyl group in the distal beta-heme pocket forms a hydrogen bond with the backbone carbonyl of [beta]His63 and is within hydrogen-bonding distance of the ND atom of [beta]His63.
The polymeric additive includes a polymeric backbone having substituents attached thereto, wherein the substituents include at least one urethane linked nitrogen bonded side chain having about 5 carbon atoms or more and a terminal methyl group and at least one oxygen linked water solubilizing group.
Tocotrienols are a form of vitamin E, with an unsaturated isoprenoid side chain rather than the saturated side chain of tocopherols.