For example, a macrophage that has ingested RBCs is termed an erythrophage; if the RBCs have been ingested for more than 72 hours, the iron in the RBCs is visible and the cell is termed a siderophage
. The finding of erythrophages and siderophages
has different significance in various fluids.
Macroscopic examination of the sellar content showed a non-hemorrhagic grayish and soft tumorous mass without any traces of normal tissue, while histopathologic examination revealed necrotic pituitary tissue surrounded by siderophages
and mononuclear inflammation cells (Fig.
There is a variable admixture of inflammatory cells, foamy macrophages, Touton giant cells, and siderophages
. Entrapped thickened, hyaline collagen bundles are seen at the peripheries of the lesion.
The internodular tissue consisted of dense fibrous tissue with myxoid areas and scattered plump myofibroblasts, plasma cells, lymphocytes, and siderophages
In fact, siderophages
, macrophages storing iron, are heavily laden with hemosiderin inside the pelvic cavity .
The intervening stroma was edematous with extravasated RBCs and siderophages
[Figures 2 and 4].
The finding was further confirmed by Prussian blue staining of broncho-alveolar lavage centrifugate which revealed hemosiderin-laden macrophages (Siderophages
Diagnosis is suggested by the triad of haemoptysis, anaemia and pulmonary infiltrates and is secured by the finding of haemosiderin-laden macrophages (siderophages
) in broncho-alveolar lavage fluid.
The periphery was devoid of endothelial or epithelial lining (pseudocyst) and consisted of siderophages
, reactive spindle cells (fibroblasts), multinucleated giant cells (osteoclasts), and bony spicules.
There were fragments of mature fibrous tissue with numerous cholesterol clefts, siderophages
, and foci of dystrophic calcification.
Hyperpigmentation of regressed KS lesions is attributed to the accumulation of dermal siderophages
. This may be cosmetically disconcerting for treated patients.
(8) It is a benign, probably reactive lesion composed of angiomatoid (vascular) nodules surrounded by sclerotic stroma, fibroblasts, myofibroblasts, and inflammatory cells (plasma cells, lymphocytes, macrophages, and siderophages