signaling cell

signaling cell

[′sig·nə·liŋ ‚sel]
(physiology)
A cell whose products induce a specific response in target cells.
References in periodicals archive ?
Therefore, molecular pathways involved in signaling cell differentiation have been studied by many researchers in order to access a population of fully differentiated cells.
With respect to the broad beneficial effects of lithium in signaling cell pathways, in the current study, the effects of several doses of lithium chloride were evaluated on dopaminergic differentiation of human immortalized RenVm cells.
The beauty of this study is that we now have a system in which we can investigate how a signaling cell uses these two genes Yorkie and Scalloped, which have never before been shown in blood, to direct specific cells to be made," said Martinez-Agosto, associate professor of human genetics.
Contact between the ligand of a signaling cell (at the top) and the NOTCH receptor of a neighboring cell (at the bottom) produces a series of proteolytic events at the extracellular and intracellular domains of the NOTCH receptor, causing the NOTCH intracellular domain (NICD) to translocate to the nucleus, activating the transcription of genes of the bHLH, Hes and Hey family through interaction with CSL transcription factor and the MAML co-activator.
The bacteria, or "bug," causing Fred's strep throat is like the extracellular signal molecule, or signaling cell, that prompts Fred to feel ill.
To be completely effective, the signal must be converted into a longer lasting one that can be delivered throughout the cell and into the nucleus to alter gene expression and relay the message of the signaling cell.
Therefore placental signaling cells can be isolated, cultured and genetically-modified independent of other cells in the mouse placenta.
Within two to four hours of preterm babies receiving a blood transfusion, we have seen elevated levels of cytokines and chemokines - signaling cells - that stimulate inflammatory responses in the body," Dr Stark said.
They determined that ephrin-B1 controls craniofacial development by signaling cells to multiply and when there is a mutation in this gene, it causes anomalies in the cell proliferation process
Gut signaling cells make up less than 1 percent of the cells of the intestinal wall, yet together these signaling cells constitute the largest hormone-releasing organ of the body, Sternini pointed out in 2007 in Current Opinion in Pharmacology.
Dopamine is secreted by signaling cells, and delivers its message by binding to receptors on the surface of receiving cells.
Because MSCs are showing themselves capable of far more than a foundation for tissue engineering, Caplan suggested the acronym should now stand for medicinal signaling cells.