Various morphological features similar to those presented here can be observed in NETs, such as spindle-shaped cells, acinar cells,
signet-ring cells, and mucin-producing cells (goblet cells) (4, 5).
Kanekura, "Extramammary Paget's disease with prominent
signet-ring cells," Journal of Dermatology, vol.
Classical adenocarcinoma is the most common histologic subtype of CRC, whereas mucinous subtype accounts for 1020% and
signet-ring cell subtype for 0.9-4% of cases of CRC [20].
Mucinous and
signet-ring cells histological variants are even rarer [2,3].
Autopsy results supported the diagnosis of lymphangitic carcinomatosis with
signet-ring cell morphology.
(5,12) Similarly, one report describes response to palliative chemotherapy with the FOLFOX-6 regimen plus bevacizumab in the treatment of typical bladder adenocarcinoma, but ours is the first to describe response of the
signet-ring cell variant specifically, and with the use of FOLFOX-6 alone.
Signet-ring cell lymphoma in the orbit: a case report and review.
Cases of primary colorectal
signet-ring cell carcinoma metastatic to the tonsil are extremely rare.
DALLAS --
Signet-ring cell colorectal carcinomas are associated with poorer outcomes than are either mucinous carcinomas or non-signet-ring cell, nonmucinous forms of colorectal adenocarcinomas, Dr.
DALLAS --
Signet-ring cell colorectal carcinomas are associated with poorer outcomes than are either mucinous carcinomas or non-signetring cell, nonmucinous forms of colorectal adenocarcinomas, Dr.
The pathology department reported a poorly differentiated adenocarcinoma with
signet-ring cell differentiation (Figure 2).
Lal et al., "
Signet-Ring Cell Change Versus
Signet-Ring Cell Carcinoma: A Comparative Analysis," The American Journal of Surgical Pathology, vol.