sodium fluorescein


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sodium fluorescein

[′sōd·ē·əm flu̇′res·ē·ən]
(organic chemistry)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The investigators enrolled 176 participants (174 completed the trial) and randomly assigned them to receive 1 of 4 modalities: 1) normal saline as a bladder distention medium (control), 2) 10% dextrose as a bladder distention medium, 3) 200 mg oral phenazopyridine given 30 minutes prior to cystoscopy, or 4) 50 mg IV sodium fluorescein at the start of cystoscopy.
An alternate compound, sodium fluorescein, also highlights the tumour and its margins, by accumulating in areas of disrupted blood brain barrier.3,4 Its fluorescence can be detected with the help of Yellow 560 nm and Blue 400 nm filters on Pentero (Carl Zeiss(tm)) and Leica(tm) operative microscopes respectively.
To evaluate functionality of the diffusional barrier in more detail, the transport of sodium fluorescein (NaFlu), a hydrophilic molecule typically used to evaluate paracellular transport, was monitored.
SCLLs entrapping a hydrophilic fluorescent probe, sodium fluorescein (FL), and incubating with three fluorescent probes with different lipophilicities were used to observe SCLL leakage and fluidity, respectively, and compared with conventional in vitro skin permeation tests as well as skin impedance test to determine the effectiveness of this HTS technology.
After the induction of anesthesia and before skin incision, 2-3 mg/kg bodyweight (3 mg/kg in first 28 cases and 2 mg/kg in late 10 cases) of 20% solution of sodium fluorescein (Guangzhou Baiyun Shan Ming Xing Pharmaceutical Company, China, National Drug number: H44023400) diluted to 1% was administered by bolus intravenous injection.
WASHINGTON -- Sodium fluorescein is proving to be an excellent agent for helping to verify ureteral efflux during intraoperative cystoscopy, Dr.
Here sodium fluorescein solution is added to the epithelial side of the chamber and the permeability of the fluorescent compound is quantified by measuring absorbance at 490nm.
Five well-known methods involving the use of fluorescent tracer (sodium fluorescein and rhodamine) and saline tracer (sodium chloride, NaCl), which are method of moments (Fischer, List, Koh, Imberger, & Brooks, 1979), routing procedure or propagation method (Fischer et al., 1979; French, 1985), Chatwin's graphical method (Krenkel, 1962), peak concentration method (Rutherford, 1994) and crown concentration method (Devens, Barbosa Jr, & Sivla, 2006);
Two percent (2%) sodium fluorescein solution was gently instilled into the inferior fornix of the subject.
A 10% sodium fluorescein (Fluoresceina sodica 100mg [ml.sup.-1] injetavel, Novartis) was applied, intravenously, in bolus, at a 10mg [kg.sup.-1] dose.
[10] If there is edema in the macula or the central fovea, where it threatens central vision, one must first identify the leaking microvascular lesions by injecting sodium fluorescein angiography intravenously and photographing retinal vessels by fundus camera.
Then the nontargeted and targeted nanoparticles were loaded with sodium fluorescein instead of etoposide by the same method as mentioned above for drug-loaded SLNs.

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