sodium thiosulfate


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

sodium thiosulfate,

Na2S2O3, colorless crystalline compound that is more familiar as the pentahydrate, Na2S2O3·5H2O, an efflorescent, monoclinic crystalline substance also called sodium hyposulfite or "hypo." Sodium thiosulfate is readily soluble in water and is a mild reducing agent. Because it dissolves silver salts, its major use is in photography for developing film. It is also used in chrome-tanning leather and in chemical manufacture. Sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. It is also produced from sodium carbonate, sulfur dioxide, and sulfur by a process that involves several steps.

Sodium Thiosulfate

 

(also sodium hyposulfite, N2S2O3), colorless crystals freely soluble in water (41.2 percent by weight at 20°C, 69.9 percent at 80°C). Sodium thiosulfate forms several crystal hydrates, of which only the pentahydrate Na2S2O3·5H2O is used in industry and in the laboratory.

Sodium thiosulfate is obtained by boiling a solution of sodium sulfite with sulfur in powder form: Na2SO3 + S = Na2S2O3. It is used as a fixing agent in photography and for determinations of iodine in iodometry; it also finds use in the textile industry and in other fields. In medicine, sodium thiosulfate is used as a desensitizer, an antiphlogistic, and an antitoxic agent. The antitoxic effect is based on the ability of sodium thiosulfate to form nontoxic compounds, including sulfites with arsenic, thallium, mercury, and lead and rhodanides with hydrocyanic acid. Sodium thiosulfate is usually administered intravenously (as a 10–30 percent solution) to those suffering from arthritis, dermatosis, poisoning, and illnesses related to allergies.

sodium thiosulfate

[′sōd·ē·əm ‚thī·ə′səl‚fāt]
(inorganic chemistry)
Na2S2O3·5H2O White, translucent crystals or powder with a melting point of 48°C; soluble in water and oil of turpentine; used as a fixing agent in photography, for extracting silver from ore, in medicine, and as a sequestrant in food. Also known as sodium hyposulfite; sodium subsulfite.
References in periodicals archive ?
Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease andcalciphylaxis-calcific uremic arteriolopathy: The emerging role of sodium thiosulfate.
where w is the weight in grams of the sample, N is the normal concentration of the sodium thiosulfate solution used (in mol [L.
Sodium thiosulfate and biphosphonates have demonstrated beneficial outcomes in the management of calciphylaxis (Raymond & Wazny, 2008).
5% sodium hypochlorite, which was inactivated with 5% sodium thiosulfate.
The purpose of this article is to describe the use of sodium thiosulfate, bisphosphonates and cinacalcet (Sensipar[R]) for the treatment of calciphylaxis in patients with chronic kidney disease.
The company currently has multiple products in the clinical stage of development, including ADH-1 (Exherin(TM)), eniluracil and sodium thiosulfate (STS).
21) There is a recent report of a successful treatment of calciphylaxis with IV sodium thiosulfate in a patient that had failed conventional measures.
Based upon the variation in pigment hues between the NA, TSA, and TSI slants, the possibility of peptones, ferrous sulfate, and sodium thiosulfate serving as repressors exists since they are the ingredients which differ between media.
Add sodium thiosulfate to neutralize any chlorine residual in the water.
To prevent chemotherapy-induced high-frequency ototoxicity associated with the intra-arterial injection of carboplatin in conjunction with BBBD, she received Intravenous sodium thiosulfate at 4 and 8 hours following her BBBD.
Use 20 cc of a 10 percent solution of sodium thiosulfate to which 10 cc of a 10 percent solution of nitrite has been added.
25% sodium hypochlorite) was used for disinfection, and sodium thiosulfate (0.