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Hives or nettle rash; a skin condition characterized by the appearance of intensely itching wheals or welts with elevated, usually white centers and a surrounding area of erythema. Also known as hives.



nettle rash, an allergic reaction characterized by the sudden and rapid appearance on the skin (sometimes also on the laryngeal mucosa) of intensely itching wheals.

Urticaria is often caused by the sting of the nettle and certain other plants. Insect bites, temperature, and chemical agents are also among its causes. Other factors include parasitic worms, chronic constipation, liver and kidney diseases, and allergic sensitivity to some foods (for example, strawberries, citrus fruits, eggs, mushrooms, preserves, certain fish, pork, and chocolate). Urticaria is sometimes caused by hypersensitivity to drugs (especially to those of chemical origin). The rash associated with the condition is a manifestation of the inflammatory reaction and edema of the skin that result from a sudden increase in the permeability of the capillaries in the area. This results from the liberation of histamine from the mast cells of the skin by allergic alteration. Urticaria usually disappears without a trace within a few hours, although it sometimes recurs. It is treated by purgation (by enemas, laxatives), special diet (mostly milk and vegetables, with limited salt intake), and desensitizing and anti-histaminic agents.


Pavlov, S. T. Kozhnye i venericheskie bolezni, 2nd ed. Moscow, 1969.


References in periodicals archive ?
Classification of urticaria Type Subtype Spontaneous urticaria Acute and chronic spontaneous urticaria Physical urticaria Cold urticaria Delayed pressure urticaria Hot urticaria Solar urticaria Dermographism Vibration urticaria Other Aquagenic urticaria Cholinergic urticaria Contact urticaria Exercise induced anaphylaxisurticaria Table 2.
Diagnosis and treatment of solar urticaria. Dermatol Therapy 2003; 16:52-6.
The afamelanotide implant (Scenesse) is also in clinical trials for more common diseases, including vitiligo, solar urticaria, and polymorphous light eruption, as well as for prevention of actinic keratoses and squamous cell carcinomas in organ transplant recipients.
METHODS: 26 patients with polymorphic light eruption and two with solar urticaria were recruited to enter the study.
EpiTan is also investigating Melanotan as a therapeutic agent for UV-induced skin allergies such as PMLE and solar urticaria. PMLE is a significant UV-induced skin allergy in northern latitudes and the company expects to begin trials in Europe in early 2004 to examine the ability of Melanotan to alleviate or cure this disorder.
Another type of hives is called solar urticaria. It is caused by exposure to sunlight or to a sunlamp and a reaction can occur within one to three minutes.