Solubilization


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Solubilization

 

a colloidal dissolution involving the spontaneous and reversible penetration of a low-molecular-weight substance (solubilizate), which is slightly soluble in a particular liquid medium, into micelles of a surfactant or globules of a high-molecular-weight compound present in the medium. Solubilization is a typical property of such association colloids as aqueous solutions of soaps and synthetic detergents at concentrations greater than the critical micelle concentration and solutions of proteins and certain synthetic polymers. Solubilization of oils, fats, and hydrophobic organic liquids occurs in systems with aqueous media; solubilization of water and, less often, other polar substances occurs in systems with hydrocarbon media.

Solubilization plays an important role in such technological processes as micellar catalysis, the production of synthetic rubber by means of emulsion (latex) polymerization, textile cleaning, and the manufacture of lubricants, pesticides, and certain pharmaceuticals and foodstuffs. Solubilization is also important in biological processes; during digestion, for example, fats are solubilized by substances in the bile.

References in periodicals archive ?
Solubilization of zinc salts by a bacterium isolated from the air environment of a tannery.
The solubilization extent for each molecule by each excipient is demonstrated in Figure 1.
2] fixation and K solubilization are of great relevance, especially for extensive areas, where the lack of nutrient replacement, such as N and K have been identified as one of the causes of degradation (Bonfim-Silva & Monteiro, 2006).
Among these 28 isolates were selected based on zone of potassium solubilization.
For the solubilization experiment, protocols described in the literature (Zhou & Huang, 2006; 2007) were followed with adaptations related to rock/extractant relationships, molar concentrations, rock-extractant contact times, and temperature.
Equation 3 gives the calculation of mass yield (MY) which considers the biomass's initial and final weights (before and after the pretreatment, respectively), whereas Equation 4 considers solubilization by a relationship between TSS ([degrees]Brix) and waste mass.
All the selected isolates FA-4 FA-3 FA-2 and FA-8 showed considerably diverse zone for Zn solubilization (59.
The solubilization efficiency of 16 isolates was measured at the end of 7 days incubation.
Sakhare, "Formulation and evaluation of hydrotropic solubilization based suspensions of Griseofulvin," International Journal of Pharma Sciences and Research, vol.
Baker[R] Polysorbate 20 and 80 are designed to improve solubilization and stability in a variety of biopharmaceutical and small-molecule drug formulations.