Solubilization

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Solubilization

 

a colloidal dissolution involving the spontaneous and reversible penetration of a low-molecular-weight substance (solubilizate), which is slightly soluble in a particular liquid medium, into micelles of a surfactant or globules of a high-molecular-weight compound present in the medium. Solubilization is a typical property of such association colloids as aqueous solutions of soaps and synthetic detergents at concentrations greater than the critical micelle concentration and solutions of proteins and certain synthetic polymers. Solubilization of oils, fats, and hydrophobic organic liquids occurs in systems with aqueous media; solubilization of water and, less often, other polar substances occurs in systems with hydrocarbon media.

Solubilization plays an important role in such technological processes as micellar catalysis, the production of synthetic rubber by means of emulsion (latex) polymerization, textile cleaning, and the manufacture of lubricants, pesticides, and certain pharmaceuticals and foodstuffs. Solubilization is also important in biological processes; during digestion, for example, fats are solubilized by substances in the bile.

References in periodicals archive ?
The HTS approach shortens the time necessary to identify which excipients can adequately solubilize a compound, as well as which excipients a compound can remain stable in.
Among the studied strains, it is possible to highlight UNIFENAS 100-94, which presented a high capacity to solubilize K of phonolite rock powder when grown in both studied carbon sources, indicating greater metabolic versatility, having a good potential to solubilize K in the soil.
Thus, in present study PL 11, PL 13 and PL 16 were found to be more efficient bacterial isolates to solubilize TCP.
None of the strains of the genus Azospirillum was able to solubilize high concentrations of P in comparison with the other evaluated strains.
Rahnella aqualitis, a bacterim isolated from soybean rhizosphere, can solubilize hydroxyapatite.
Some microbes are able to enhance the bioavailability of hydrophobic pollutants by biosynthesis of compounds that solubilize the target substrate.
We studied the influence of different concentrations of various detergents and temperatures on the fluidity of membranes, and compared these data with the ability of the detergents to solubilize mAChR.
A sample is placed in an extraction cup and a known pressure of a supercritical fluid is pumped through the vessel to solubilize analytes from the bulk sample matrix into the supercritical fluid.
We designed an HSM by intuition and empirically tested it to see whether it could solubilize pieces of rubber vulcanizate in conjunction with added material to form a rubbery matrix.
When you dissolve soap in water, the mixture forms tiny [droplets], called micelles, which will solubilize oil and grease," Beckman explains.
In the experiments reported below and illustrated in the figures, the zwitterionic detergent CHAPS was used to solubilize the FMRFamide receptor from SQM.