Van Wyk, "Somatomedin
: proposed designation for sulphation factor," Nature, vol.
Cunningham  and Ganong  stated that growth hormone perform its effects on target tissues through liberation of somatomedin
C also called [IGF.sub.1] and [IGF.sub.2].
Gene Gene names, alternative abbreviations Fold Direction symbol change * 1L-6 Interleukin 6 (interferon, beta 2) 1.66 down CRP C-reactive protein, pentraxin-related 1.53 down IL-7 Interleukin 7 1.67 up CX3CL1 Chemokine (C-X3-C motif) ligand 1 2.27 down 1GF2 Insulin-like growth factor 2 2.02 down (somatomedin
A) FZD1 Frizzled homolog 1 (Drosophila) 2.12 down TACR1 Tachykinin receptor 1, substance P 2.37 down receptor CTSG Cathepsin G 2.11 down CD80 CD80 molecule 1.86 down CD86 CD86 molecule 2.27 down HYAL1 Hyaluronoglucosaminidase 1 1.5 up HSPG2 Heparan sulfate proteoglycan 2 1.51 up (Perlecan) TNR Tenascin R (restrictin, janusin) 1.53 up SPON1 Spondin 1, R-spondinl extracellular 1.88 up matrix protein * Fold-change from baseline was significant at p < 0.05.
IGF-I, also called somatomedin
C, is a small polypeptide hormone with an approximate molecular weight of 7kDa .
* Deficiency of serotonin, tryptophan, norepinephrine, dopamine, histidine, methionine, and somatomedin
IGF-1 is also called somatomedin
C, a small 70-amino acid polypeptide with a molecular weight of 7649 kDa (5).
Its other names include IGF-1 (insulinlike growth factor type 1), somatomedin
, and sulfation factor.
Effect of zinc supplementation on growth hormone secretion, IGF-I, IGFBP-3, somatomedin
generation, alkaline phosphatase, osteocalcin and growth in prepubertal children with idiopathic short stature.
This mechanism explains the close relationship between altered zinc level and plasma insulin like growth factor (somatomedin
Mueller, "The effects of insulin and growth hormone on the release of somatomedin
by the isolated rat liver," Endocrinology, vol.
Octreotide Acetate Injection, a Somatostatin Analog, is indicated to reduce blood levels of growth hormone and IGF-I (somatomedin
C) in acromegaly patients who have had inadequate response to or cannot be treated with surgical resection, pituitary irradiation, and bromocriptine mesylate at maximally tolerated doses, concluded the company.
Other pituitary hormones including somatomedin
(c-IGF1), growth factor and prolactin were within normal limits.