spherocyte


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to spherocyte: spherocytosis, target cell

spherocyte

[′sfir·ə‚sīt]
(pathology)
A spherical red blood cell.
Mentioned in ?
References in periodicals archive ?
However, on the next day, spherocyte percentage increased (16%) but still remained below the first spherocyte value.
The number of spherocytes was reduced, whereas other pathological forms of erythrocytes related to reversible forms such as stomatocytes and echinocytes were more frequent (Figure 1(d)) in the patient group after the treatment.
Arsenic-induced echinocytic transformation of erythrocyte was confirmed by SEM analysis, which showed distinct membrane blebbing, increased number of spherocytes and microcytosis, but these were almost absent in the control group (figure 2A and B).
In sepsis, inflammation resulting from ROS production promotes morphological changes in erythrocytes, with the appearance of spherocytes, cup-shaped cells, and especially echinocytes.
gondii infection, RBC destruction does not appear to be a mechanism for anemia, as there are no detectable spherocytes or schistocytes, hallmarks of such destruction, [sup][39] in peripheral blood smears from infected mice (data not shown).
Haemolysis was confirmed by the detection of marked numbers of schistocytes, moderate numbers of spherocytes and mild polychromasia on blood film, and elevated serum lactate dehydrogenase and bilirubin (Figures 1 and 2).
The peripheral blood film showed dimorphic picture with polychromasia, nucleated RBCs and spherocytes. Direct antiglobulin test was strongly positive.
1) showed a leukoerythroblastic picture with marked polychromasia, large number of circulating nucleated red blood cells and marked poikilocytosis including blister cells, spherocytes and echinocytes, consistent with oxidative hemolysis.
The blood smear showed a severe red cell agglutination with moderate number of spherocytes. The reticulocyte count was initially normal.
The spherocytes tend to get trapped in the spleen and are broken up there.
Peripheral smear showed severe anisocytosis, macrocytosis with microcytic RBC population and spherocytes, Nucleated RBCs= 3/ 100 WBCs, neutrophilia with hypersegmented neutrophils, metamyelocytes and myelocytes.
Blood film was stained by May - Grunwald - Giemsa stain and peripheral smear examination was carried out for differential leucocyte count (DLC), identification of spherocytes, schistocytes, thrombocytopenia and platelet anisocytosis.