Spike Potential

Also found in: Dictionary, Thesaurus, Medical.

Potential, Spike


a large and sudden change in electrical potential that accompanies excitation in nerve and muscle cells and fibers. In physiology, the term “spike potential” is often used as a synonym for action potential. In clinical electroencephalography spike potential refers to gross potentials reaching 10 milliseconds in duration that are outwardly similar to the action potential of a nerve. These potentials are detected in an electrocorticogram taken with certain pathological disturbances, particularly epilepsy.

References in periodicals archive ?
As observed in Figure 2, in reverse EEG potential averaging, all subjects showed defined potentials in the saccadic LP, related to saccade initiation--P -1, N--1--and spike potentials (SP).