Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Wikipedia.
Related to Spondylitis: spondylosis, spondylolysis


Inflammation of the vertebrae. Also known as ankylosing spondylitis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a chronic inflammation of man affecting the vertebrae. Spondylitis is usually caused by tuberculosis; it may sometimes be caused by other infections, for example, by staphylococcal or syphilitic infections.

Tuberculous spondylitis primarily affects children under ten years of age, with the thoracic vertebrae being involved in 60 percent of cases. The causative agent is carried with the blood flow to the highly vascularized spongy substance of the bone of a vertebra. Penetrating the spongy substance, it stimulates the development of the tuberculous process. Trauma to the spine does not cause spondylitis, although it does help to exacerbate the disease and manifest the latent process. A tuberculous granuloma that forms in a vertebral body causes the gradual destruction of the bony substance of the vertebra. Purulent and necrotic masses descend along the spine, forming a wandering abscess that may burst and create fistulas.

Tuberculous spondylitis develops slowly. At first, bone changes may be detected only through roentgenologic examination. The spread of the process to the tissues near the spine produces pain that intensifies with movement. Increasing spinal deformity is the most common cause of humpbacks. Paralyses, pain along the course of the nerves, and sensory disturbances may result from the compression of the spinal cord or the roots of spinal nerves by deformed vertebral bodies.

Spondylitis caused by a pyogenic infection may progress very rapidly, being characterized by high temperatures and intoxication. The destruction of vertebral bodies is less extensive with this form than with tuberculous spondylitis.

Tuberculous spondylitis is prevented and treated in the same manner as tuberculosis. Prolonged immobilization of the spine in a special plaster bed is effective in the early stage of the disease. The purulent and necrotic masses may be removed surgically. Immobilization, surgery, and antibiotics are used to treat other forms of spondylitis.


Krasnobaev, T. P. Kostno-sustavnoi tuberkulez u detei, 2nd ed. Moscow, 1950.
Chaklin, V. D. Ortopediia, books 1–2. Moscow, 1957.
Kornev, P. G. Klinika i lécheme kostno-sustavnogo tuberkuleza. Moscow, 1959.
Mnogotomnoe rukovodstvo po ortopedii i travmatologii, vol. 1. Moscow, 1967.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Malley et al., "Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis," Arthritis Care and Research, vol.
Suh et al., "Dickkopf-1 level is lower in patients with ankylosing spondylitis than in healthy people and is not influenced by anti-tumor necrosis factor therapy," Rheumatology International, vol.
Reveille, "Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondylarthritis," Clinical Rheumatology, vol.
Comorbidity profiles among patients with ankylosing spondylitis: a nationwide population-based study.
'Ankylosing spondylitis is not rare, but it's important we find them because this usually afflicts people in their most productive years,' said Dr.
Not only does vitamin D play an important role in ankylosing spondylitis, it plays an important role in all autoimmune diseases, such as Hashimoto's thyroiditis, systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes, and irritable bowel disease.
"Ankylosing spondylitis is a disease that usually affects young men and most patients are of an age less than 40 years.
Spondyloarthropathies (SpA) are a group of diseases in which rheumatoid factor and anti-nuclear antibodies are negative and presenting with spinal, articular, and extra-articular symptoms.1 Ankylosing Spondylitis (AS) is a major rheumatic disorder of the (SpA) group that mainly influences the axial spine and sacroiliac joints.
Clinical manifestations such as uveitis, aphthae, arthritis, enthesitis and clinical indices such as Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrologie Index (BASMI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Ankylosing Spondylitis Quality of Life (ASQOL) were evaluated.
Karachi: In solidarity and awareness of the 'Ankylosing Spondylitis'- AS disease and its high impact on lives of millions of patients suffering globally, Novartis in Collaboration with the Pakistan Society of Rheumatology and Arthritis Care Foundation, holding a Press Conference on 5th May 2018 at Avari Towers.
Summary: Persistent back pain with stiffness in the morning can be because of ankylosing spondylitis, says doctor