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see fungal infectionfungal infection,
infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals

Many fungal infections, or mycoses, of humans and animals affect only the outer layers of skin, and although they are sometimes
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a chronic disease of humans and animals caused by a fungus of the genus Sporotrichium; a type of mycosis.

In humans the disease affects the skin, subcutaneous tissue, and, less frequently, the mucous membrane and the internal organs. The causative agents of sporotrichosis have been found in plants (shrubs, grass, hay, and cereals), in soil, in street dust, and in food products. The fungus enters the body through injured skin and through the respiratory and gastrointestinal tracts. The infection is spread via the lymph and blood. Numerous hard, painless lymph nodes appear, mainly on the upper extremities. The nodes gradually become soft and open up, forming ulcers that leave irregular scars. The internal organs may be affected in the form of sepsis.

Diagnosis is made on the basis of bacterioscopy, tissue biopsy, and allergic cutaneous reactions. Sporotrichosis is treated with potassium or sodium iodide, or antibiotics; it may be treated locally with aniline dyes or ichthammol. Prophylaxis consists of thorough and timely treatment of injured skin.

In animals the causative agent of sporotrichosis attacks the organism through traumatized skin (wounds and abrasions). Horses, mules, dogs, and cats are mainly affected. The course of the disease is chronic. In horses the skin and lymphatics in the region of the neck and the extremities are affected. Pustules, ulcers, and abscesses are formed. The nodes that erupt on the skin are initially hard and painless; they become soft, forming fistulas that secrete pus. Necrotic lymph nodes (abscesses) subsequently form ulcers with raised edges. In dogs, cutaneous nodes and ulcerations appear over the entire body. Treatment consists of the use of iodine and sulfanilamide preparations. Specific prophylactic measures have not been developed.


Mashkilleison, L. N. Infektsionnye i parazitarnye bolezni kozhi, 2nd ed. Moscow, 1964.
Spesivtseva, N. A. Mikozy i mikotoksikozy, 2nd ed. Moscow, 1964.



A granulomatous fungus disease caused by Sporotrichum schenckii, with cutaneous lesions along the lymph channels and occasionally involving the internal organs. Also known as de Beurmann-Gougerot disease; Schenk's disease.
References in periodicals archive ?
Itraconazole is the drug of choice for uncommon IFI like mild/moderate coccidioidomycosis, paracoccidioidomycosis, histoplasmosis, blastomycosis, sporotrichosis, and pseudallescheriasis.
Sporotrichosis is a rare disease caused by the dimorphic fungus Sporothrix Schenckii sensu lato [4], and molecular studies have shown that this species is made up of a complex of 6 different phylogenetic species.
It was used the 16345 strain of Sporothrix schenckii isolated from a pulmonary human infection of sporotrichosis (Baltimore, MD), courtesy of Reference Materials Laboratory of the Oswaldo Cruz Foundation.
Mde Muniz et al., "Molecular characterization of Sporothrix schenckii isolates from humans and cats involved in the sporotrichosis epidemic in Rio de Janeiro, Brazil," Memorias do Instituto Oswaldo Cruz vol.
Where leishmaniasis and sporotrichosis are endemic, they must be excluded.
Sporotrichosis: This disease is caused by Sporothrix schenckii, and most infections are opportunistic, self-limiting, and cutaneous.
Sporothrix schenckii isolated from domestic cats with and without sporotrichosis in Rio de Janeiro, Brazil.
3), leprosy, subcutaneous mycosis as mycetoma or sporotrichosis, as well as deforming genodermatoses, are of particular concern--not only do they cause marked morbidity but they may lead to death.