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see fungal infectionfungal infection,
infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals

Many fungal infections, or mycoses, of humans and animals affect only the outer layers of skin, and although they are sometimes
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a chronic disease of humans and animals caused by a fungus of the genus Sporotrichium; a type of mycosis.

In humans the disease affects the skin, subcutaneous tissue, and, less frequently, the mucous membrane and the internal organs. The causative agents of sporotrichosis have been found in plants (shrubs, grass, hay, and cereals), in soil, in street dust, and in food products. The fungus enters the body through injured skin and through the respiratory and gastrointestinal tracts. The infection is spread via the lymph and blood. Numerous hard, painless lymph nodes appear, mainly on the upper extremities. The nodes gradually become soft and open up, forming ulcers that leave irregular scars. The internal organs may be affected in the form of sepsis.

Diagnosis is made on the basis of bacterioscopy, tissue biopsy, and allergic cutaneous reactions. Sporotrichosis is treated with potassium or sodium iodide, or antibiotics; it may be treated locally with aniline dyes or ichthammol. Prophylaxis consists of thorough and timely treatment of injured skin.

In animals the causative agent of sporotrichosis attacks the organism through traumatized skin (wounds and abrasions). Horses, mules, dogs, and cats are mainly affected. The course of the disease is chronic. In horses the skin and lymphatics in the region of the neck and the extremities are affected. Pustules, ulcers, and abscesses are formed. The nodes that erupt on the skin are initially hard and painless; they become soft, forming fistulas that secrete pus. Necrotic lymph nodes (abscesses) subsequently form ulcers with raised edges. In dogs, cutaneous nodes and ulcerations appear over the entire body. Treatment consists of the use of iodine and sulfanilamide preparations. Specific prophylactic measures have not been developed.


Mashkilleison, L. N. Infektsionnye i parazitarnye bolezni kozhi, 2nd ed. Moscow, 1964.
Spesivtseva, N. A. Mikozy i mikotoksikozy, 2nd ed. Moscow, 1964.



A granulomatous fungus disease caused by Sporotrichum schenckii, with cutaneous lesions along the lymph channels and occasionally involving the internal organs. Also known as de Beurmann-Gougerot disease; Schenk's disease.
References in periodicals archive ?
Treatment of disseminated sporotrichosis consists of initial treatment with intravenous amphotericin B, followed by oral itraconazole.
Until recently the standard therapy for lymphocutaneous and cutaneous sporotrichosis was saturated solution of potassium iodide concentration.
In Western Australia, sporadic cases have occurred for many years in the southwest, particularly in the wheat-growing areas (Figure 1), but in the year 2000 an increase in the number of cases of sporotrichosis was noted (6).
From 1987 to 1997, before the current emergence of sporotrichosis in Brazil, only 13 cases of human sporotrichosis had been recorded at the Evandro Chagas Clinical Research Institute (IPEC) in Rio de Janeiro (6).
Sporotrichosis has been described from North and South America, Europe, and Japan.
Subcutaneous mycoses: chromoblastomycosis, sporotrichosis and mycetoma.
Where leishmaniasis and sporotrichosis are endemic, they must be excluded.
We categorized sporotrichosis-associated hospitalizations as lymphocutaneous, pulmonary, or arthritic sporotrichosis by using ICD-9-CM codes suggestive of lymphocutaneous disease (289.
Among the fungal causes of death in the AFMR, sporotrichosis was the least common.
3), leprosy, subcutaneous mycosis as mycetoma or sporotrichosis, as well as deforming genodermatoses, are of particular concern--not only do they cause marked morbidity but they may lead to death.
Most of deep mycoses are infections of other system with secondary cutaneous lesion which includes maduromycosis, histoplasmosis, blastomycosis, sporotrichosis, phaeohypomycosis and coccidiomycosis.