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or diethylstilbestrol
, synthetic nonsteroid female sex hormone having the same physiological effects as estrogen. In the 1940s and 50s DES was mistakenly believed to reduce the risk of miscarriage and was routinely prescribed for pregnant women believed to be at
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Stilboestrol and stuttering priapism in homozygous sickle-cell disease.
This flawed science has resulted, for instance, in the drug diethylstilboestrol or stilboestrol, a synthetic ostrogen for checking cancer of the prostrate and preventing miscarriages but was found to cause transplacental cancer twenty years after the drug was first marketed (pp.
The drug, called stilboestrol or diethylstillboestrol (DES), was given to thousands of British women between 1941 and 1975 when it was withdrawn because of concerns about its safety.