stratum granulosum


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stratum granulosum

[′strad·əm ‚gran·yə′lō·səm]
(histology)
A layer of granular cells interposed between the stratum corneum and the stratum germinativum in the thick skin of the palms and soles.
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Microscopically six animals showed mild hyperplasia with cells having pyknotic and darkly stained nuclei in stratum granulosum of epidermis and appendages in the dermis.
On EM, the stratum granulosum contains more lamellar granules and a larger transition cell layer, and immunochemical analysis reveals an increased expression of genetic markers associated with keratinization.
Specifically, we found intracellular zoospore-carrying sporangia within the stratum corneum and stratum granulosum of toe and skin samples.

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