streptokinase


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Related to streptokinase: urokinase

streptokinase

[¦strep·tō′kī‚nās]
(biochemistry)
An enzyme occurring as a component of fibrinolysin in cultures of certain hemolytic streptococci.
References in periodicals archive ?
The patients included in the study were randomized into two groups--30 patients in the study (Cases) group were thrombolysed with 7.5 lakh units of streptokinase (half dose) over thirty minutes while the rest 30 patients in the control group were administered 1.5 million units of streptokinase (Conventional full dose) over one hour.
Thrombolysis in the developing world: is there a role for streptokinase? Int J Stroke 2013; 8: 560-5.
Production and purification of streptokinase by protected affinity chromatography.
Humoral and cellular immune responses up to 7.5 years after administration of streptokinase for acute myocardial infarction.
The mean age of male and female patients treated with streptokinase was 52.3 [+ or -] 8.93 and 60.2 [+ or -] 8.50 years, respectively.
The particularities of this case consists of a young patient with recurrent deep venous thrombosis and massive pulmonary embolism, with confirmed thrombophilia (heterozygous for MTHFR C 667 T mutation), with recurrent embolism despite catheter-directed thrombolysis, slow clinical amelioration under prolonged streptokinase infusion with no significant changes in thrombus burden at discharge, and a good evolution after chronic oral anticoagulation.
Streptokinase is a pregnancy Category C drug, meaning that no adequate studies have been done in humans but potential benefits outweigh risks.
Thrombolytic activity of water (control), streptokinase and various extracts of the whole plant of Andrographis paniculata Activity Water n-hexane Ethanol Crude Strepto- soluble soluble ethanol kinase fraction fraction extract Thrombolytic 50.14 30.38 60.92 * 65.97 * 96.58 *** activity (% of Lysis) * = P<0.05; *** = P<0.01 Table 3.
The streptokinase era dates back to 1933, while Tillett and Garner [24] discovered the agent through sheer serendipity, who called it fibrolysin.
de Nucci, "Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay," Brazilian Journal of Medical and Biological Research, vol.
Compared to streptokinase, fibrin-specific thrombolytic agents mimic the human tissue plasminogen activator and directly activate the conversion of plasminogen to plasmin, rapidly initiating fibrinolysis (Adams & Holland, 2011; Kee et al., 2012; Vallerand et al., 2012).
Delayed rupture of the spleen and streptokinase therapy.