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A true neoplasm composed of bizarre and chaotically arranged tissues that are foreign embryologically as well as histologically to the area in which the tumor is found.



a neoplasm occurring in man and animals that results from the impaired embryonic development of tissues. Found mainly in children and adolescents, it is localized in the sex glands and occasionally in other organs and parts of the body. A teratoma generally consists of different types of tissue, including connective, epithelial, muscular, and neural tissue, and may include such differentiated derivatives of these tissues as teeth and hair.

The most complex teratomas in terms of composition and structure are those that have developed from early blastomeres or from primary sex cells that are totipotential, or able to develop into any type of body tissue. Teratomas that arise at later stages of embryonic development (after gastrulation) are limited in composition by the formative potential of the embryonic germ layer or organ from which the teratomas originate. Simple, relatively benign teratomas are distinguished from teratoblastomas— malignant tumors composed of tissues of embryonic structure and lacking a tendency to differentiate. Simple teratomas are also distinguished from teratoids—developmental defects that are not tumors but that may develop into tumors. Teratomas may become carcinomas or sarcomas.


Klinicheskaia onkologiia detskogo vozrasta. Edited by M. V. Volkov. Moscow, 1965. (Contains bibliography.)
References in periodicals archive ?
Imaging of gynecological disease (4): clinical and ultrasound characteristics of struma ovarii. Ultrasound Obstet Gynecol.
(70) In gynecologic pathology, however, this strict differentiation is not possible, since monodermal ovarian teratomas with 1-sided tissue differentiation (monophyletic teratomas), such as struma ovarii, often occur.
Unusual arrangements in dysgerminoma: empty microcystic spaces (A) mimic small cell carcinoma with hypercalcemia, while colloidfilled spaces simulate struma ovarii (B).
El struma ovarii es un tumor poco frecuente, que representa el 0,3 % de todas las neoplasias ovaricas y que corresponde al grupo de los teratomas ovaricos monodermicos con predominio de tejido tiroideo (1, 3-5).
Teniendo en cuenta los hallazgos microscopicos se hicieron los diagnosticos de struma ovarii derecho y de teratoma quistico maduro en ovario izquierdo.
Thyroid type carcinoma originating in struma ovarii (specifying the type) is the malignant counterpart of benign struma ovarii.
The common presenting symptoms of struma ovarii are abdominal pain, abdominal mass, vaginal bleeding, ascities and pseudo-meig syndrome.
Cases of struma ovarii were considered biologically malignant if any one of the 3 following criteria were met: (1) extraovarian spread was detected at presentation; (2) tumor was detected on the ovarian serosa; or (3) there was recurrence after initial surgery, regardless of histology.
Struma ovarii: a rare form of presentation and clinical review.
Struma ovarii is a teratoma composed totally or mainly of thyroid tissue.
The incidence of thyroid-type carcinoma arising in struma ovarii is difficult to assess because of the rare nature of this condition and the lack of standard criteria for diagnosis.