(2010), of the salivary glands of fluoroquinolone-treated rats, it was reported that the diameter, size, and histological structure of sublingual and submandibular glands
morphogenesis: Stage-specific expression of TGF-[alpha]/EGF, IGF, TGF-[beta], TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-[beta]2, TGF-[beta]3, and EGF-r null mutations.
Parotid gland was the most commonly involved site 106 (67.94%) followed by submandibular gland
38 (24.35%) sublingual gland 1 (1.28%) and minor salivary glands in 5 (6.41%).
Light photomicroscope results of the submandibular gland
and nasal septum.
(28), related significant changes in the morphometric evaluation of the submandibular gland
in diabetic patients, such as the widening of the size of the adenomas and granules, the reduction in mitochondrial size, the increase of the density of microfolds and protrusions throughout the luminal membranes, even though the function of the gland seems unaltered, suggesting that the morphological alterations reflect functional changes related mainly to secretory activity.
During initial stages of development, E-cadherin and catenin regulate the morphogenesis of submandibular glands
while during advanced stages of development, they make cell-cell junctions.
The specific activity of HEX in parotid glands of the control rats in the 2nd week of the experiment was significantly higher compared to submandibular glands
of these rats, whereas in the group of diabetic rats in the 2nd week of the experiment, it was considerably lower in parotid glands than in submandibular glands
are more frequently affected, but parotid, sublingual, and labial salivary glands are also involved.
A nodule in the right thyroid lobe and another in the left submandibular gland
was seen in a neck ultrasound performed in her thyroid disease follow-up.
For patients receiving radio-chemotherapy not only parotids but the mouth and submandibular glands
and organs are involved in the development of xerostomia.
Overall, submandibular gland
involvement is exceedingly rare.
Table 2: Identified proteins with expression significantly altered in rats' submandibular glands
of group exposed to Mehg (Hg).