submandibular gland

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submandibular gland

[¦səb·man′dib·yə·lər ′gland]
(anatomy)
A large seromucous or mixed salivary gland located below the mandible on each side of the jaw. Also known as mandibular gland; submaxillary gland.
References in periodicals archive ?
(2010), of the salivary glands of fluoroquinolone-treated rats, it was reported that the diameter, size, and histological structure of sublingual and submandibular glands changed.
Submandibular gland morphogenesis: Stage-specific expression of TGF-[alpha]/EGF, IGF, TGF-[beta], TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-[beta]2, TGF-[beta]3, and EGF-r null mutations.
Parotid gland was the most commonly involved site 106 (67.94%) followed by submandibular gland 38 (24.35%) sublingual gland 1 (1.28%) and minor salivary glands in 5 (6.41%).
Light photomicroscope results of the submandibular gland and nasal septum.
(28), related significant changes in the morphometric evaluation of the submandibular gland in diabetic patients, such as the widening of the size of the adenomas and granules, the reduction in mitochondrial size, the increase of the density of microfolds and protrusions throughout the luminal membranes, even though the function of the gland seems unaltered, suggesting that the morphological alterations reflect functional changes related mainly to secretory activity.
During initial stages of development, E-cadherin and catenin regulate the morphogenesis of submandibular glands while during advanced stages of development, they make cell-cell junctions.
The specific activity of HEX in parotid glands of the control rats in the 2nd week of the experiment was significantly higher compared to submandibular glands of these rats, whereas in the group of diabetic rats in the 2nd week of the experiment, it was considerably lower in parotid glands than in submandibular glands.
Submandibular glands are more frequently affected, but parotid, sublingual, and labial salivary glands are also involved.
A nodule in the right thyroid lobe and another in the left submandibular gland was seen in a neck ultrasound performed in her thyroid disease follow-up.
For patients receiving radio-chemotherapy not only parotids but the mouth and submandibular glands and organs are involved in the development of xerostomia.
Overall, submandibular gland involvement is exceedingly rare.
Table 2: Identified proteins with expression significantly altered in rats' submandibular glands of group exposed to Mehg (Hg).