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Related to Sulfatase: sulfate, Steroid sulfatase


Any of a group of esterases that catalyze the hydrolysis of sulfuric esters.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(or sulfohydrolase), any one of several enzymes belonging to the class of hydrolases. Sulfatases catalyze the decomposition of sulfuric esters, with the release of a free sulfation. They are widespread in animals, plants, and microorganisms.

The known sulfatases act on various substrates. Aryl sulfatases hydrolyze aromatic sulfuric esters, glycosulfatases hydrolyze sulfuric esters of monosaccharides and disaccharides, chondrosulfatases decompose chondroitinsulfuric acid, sterol sulfatases hydrolyze steroid sulfuric esters, and cellulose sulfatases split the sulfo group from cellulose polysulfates. Aryl sulfatases have been studied in the greatest detail.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Mucopolysaccharidosis IV A: assignment of the human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene to chromosome 16q24.
Melatonin downregulates some of the enzymes necessary for the synthesis of estrogens, such as aromatase (cytochrome P450), steroid sulfatase (STS), and 17b-hydroxysteroid dehydrogenase type 1 (17[beta]-HSD1), whereas it stimulates estrogen sulfotransferase (EST), the enzyme that inactivates estrogens.
The HLADR-presented GNS peptide has marked sequence homology with epitopes from sulfatase proteins of the Prevotella sp.
X-linked ichthyosis (XLI) is an X-linked recessive disorder with a prevalence of approximately 1:4,000, demonstrating dry, scaly skin due to a deficiency of the enzyme steroid sulfatase [1].
Lack of sulfatase enzyme would remove the GAGS from dentinal tubule site which can cause lack of integration at enamel dentinal junction.
Then 75 [micro]L of aryl sulfatase (E.C. type H1 from Helix pomatia (Sigma-Aldrich, Taufkirchen, Germany) was loaded into each column, followed by a desulfation reaction overnight (16-18 hours) at room temperature.
The internal standards were deconjugated using 5 [micro]L of [beta]-glucuronidase/sulfatase from Helix pomatia (Type HP-2, aqueous solution, [beta]-glucuronidase activity [greater than or equal to] 100000 units/mL, sulfatase activity [less than or equal to] 7500 units/mL, Sigma-Aldrich, USA).
Most of the excreted indoxyl sulfate is digested into indoxyl by indoxyl sulfatase produced by certain bacteria.
One portion of the samples was processed and analysed immediately for biological attributes: microbial biomass carbon ([C.sub.mic]) and N ([N.sub.mic]), mineralisable C ([C.sub.min]) and N ([N.sub.min]), dehydrogenase activity, fluorescein diacetate hydrolysing activity (FDHA), [beta]-glucosidase activity, aryl sulfatase activity, acid and alkaline phosphatase activity, and urease activity.
vulnificus produce diversity of destructive extracellular products including elastase, protease, hemolysin, collagenase, DNase, lipase, phospholipase, mucinase, chondroitin sulfatase, hyaluronidase and fibrinolysin (Wright & Morris, 1991; Al-Assafi et al., 2014).