133) The sulfuration of cysteine residues is only transiently observed as an intermediate during the reduction of the disulfide bond, and the intermediate is immediately attacked by a second HS-molecule and reduced to cysteine.
Another example of the activation of target proteins by sulfuration is Kelch ECH-associating protein 1 (Keap1), which binds to nuclear factor erythroid 2-related factor 2 (Nrf2) to remain in the cytosol.
As noted already, at least some of the sulfur liberated from SAMe during transsulfuration is contributed to the sulfuration
of glucosamine and the chondroitin sulfates; methylthioadenosine (MTA), one of the products of SAMe via aminopropylation, plays a role in controlling pain and inflammation.
The changes in physical properties and cure kinetics, and the improved reversion resistance suggest that either the mechanism of sulfuration
has changed, or the nature of the active sulfurating species is unique when HTS is employed.
The GTPS and BTPS samples were pressured to transparent slices at 10 MPa and 100[degrees]C using the Flat Sulfuration Machine (a compression molder).
The extruded BTPS strips were pressed to slices with a flat sulfuration machine (Beijing Plastic Machinery Factory) and the slices were placed in a sample holder for X-ray diffractometry.