Contributing factors in PUBS include female gender, debilitation, constipation, chronic catheterization, alkaline urine, chronic kidney disease, and colonization or infection with bacteria producing phosphatase or sulphatase
Gram negative bacteria producing sulphatase
and phosphatase are important in the pathogenesis of PUBs (7,8).
In vivo inhibition of oestrone sulphatase
and dehydroepiandrosterone sulphatase
Purohit et al., "Human granulosa cells are a site of sulphatase
activity and are able to utilize dehydroepiandrosterone sulphate as a precursor for oestradiol production," Journal of Endocrinology, vol.
A genetic defect has been identified in the N-acetyl-galactosamine-6-sulphate sulphatase
(GALNS gene) in Morquio's syndrome type IVA or beta-galactosidase (GLB1 gene) in Morquio's syndrome type IVB.
Urinary tract infection (uti) with bacteria possessing indoxyl phosphatase and sulphatase
enzymes, commonhyprovidencia stuarttiand rettgeri, pseudomonas auruginosa, proteus mirabilis, escherichia coli, klebsiella pneumoniae,morganella, citrobacter species, group b streptococci and enterococci (8, 13).
Her 14-year-old son Pavan has Multiple Sulphatase
Deficiency; a rare genetic condition that seriously affects his mobility and speech.
Inhibition of steroid sulphatase
by estrone-3-O-sulphamate led to a shift of the minimum effective concentration of PS against AMPA cytotoxicity from 30 to 10 microm.
Tibolone is also a sulphatase
inhibitor, blocking conversion of oestrone sulphate to oestrone, as well as stimulating local sulphotransferase activity.
Effect of storage on the acitivities of protease, urease, phosphatase, and sulphatase
in three soils under pasture.
acid phosphatase, cathepsin, ribonuclease and aryl sulphatase
in leprosy tissues.
Identification of mycobacterial isolate at species level was done by growth rate, morphology of colonies and standard biochemical tests like catalase, nitrate reduction, Tween 80 hydrolysis, aryl sulphatase
, growth on L-J medium containing 5 per cent NaCl, MacConkey agar and pigment production tests as per the manual of Centers for Disease Control and Prevention, Atlanta (4).