, rod cells, chloride cells, and blood cells were frequently occurring.
The sensory cells are spindle-shaped with darkly stained nuclei and supporting cells
that are oval and more transparent (Crofts 1929, Bevelander 1988).
In Putnam's approach, they deliver endothelial cells, which make up the vessel lining and supporting cells
Trying a new tactic, Andrew Groves of the House Ear Institute in Los Angeles and his colleagues isolated supporting cells
from the inner ears of newborn mice and put them in culture dishes.
In their latest work, the investigators found that blocking the Notch pathway increases the formation of new hair cells not from remaining hair cells but from certain nearby supporting cells
that express a protein called Lgr5.
Building on the results of that work--and early data from previous stem cell research--the team decided to focus on the role of defective communication between stem cells and their supporting cells
in the cornea.
The strategy involves activating supporting cells
which play a key role in the construction of blood vessel walls.
Researcher Matthew Frontini, from the University of Western Ontario, said yesterday: "FGF9 seemed to 'awaken' the supporting cells
and stimulated their wrapping around the otherwise fragile blood vessel wall.
This new research identifies the critical role of these supporting cells
along with the NT3 molecules that they produce.
Astrocytes are neural supporting cells
shown to be involved in neurodegenerative diseases.
Once thought irreplaceable, research in newborn mice shows that supporting cells
in the ear can turn into hair cells.