Suppression

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suppression

[sə′presh·ən]
(computer science)
Removal or deletion usually of insignificant digits in a number, especially zero suppression.
Optional function in either on-line or off-line printing devices that permits them to ignore certain characters or groups of characters which may be transmitted through them.
(electronics)
Elimination of any component of an emission, as a particular frequency or group of frequencies in an audio-frequency of a radio-frequency signal.

Suppression

 

in genetics, a phenomenon that prevents the appearance of a character resulting from mutation and that causes partial or complete restoration of the normal phenotype.

Intragenic suppression is caused by a second (suppressor) mutation in the same gene in which the first (direct) mutation occurred. Intergenic suppression is caused by a second mutation in other genes that are located at a considerable distance from the suppressed gene. In intragenic suppression, a protein coded by a given gene can reacquire functional activity, although its original structure, in contrast to true reverse mutation, or reversion, is not restored. In intergenic suppression, the normal phenotype may be restored in some cases owing to mutations that permit other means of metabolism which do not require the functioning of the given gene. In other cases, the normal phenotype may be restored as a result of mutations that alter the process by which the genetic information of the mutant gene is realized.

The phenomenon of suppression, first discovered in 1920 by the American geneticist A. H. Sturtevant, is used to study the genetic code and other aspects of molecular genetics.

REFERENCE

Stent, G. Molekuliarnaia genetika. Moscow, 1974. Chapter 6. (Translated from English.)

I. I. TOLSTORUKOV

References in periodicals archive ?
"The risk of death from sepsis due to a suppressed immune state was greatest at hospitals with the lowest volume of immunosuppressed patients with sepsis," the authors write.
He also assured the minorities and the suppressed castes that their right would be safeguarded under the leadership of Prime Minister Narendra Modi, and urged all groups that have called for a Bharat Bandh on Monday, to help maintain peace and harmony in the country.
And the suppressed setting, on an un-suppressed firearm, actually caused malfunctions.
The patients switched from the company's Phase IIIb/IV STRIIVING open-label study that evaluated the efficacy, safety and tolerability of an antiretroviral therapy (ART) to the once-daily, fixed-dose dolutegravir-based regimen, Triumeq (abacavir/dolutegravir/lamivudine) in virologically suppressed adults with HIV-1 (n=274).
TSH remained adequately suppressed on the woman's baseline dosage in 14 pregnancies (39%); these women were taking a mean daily dose of 139 mcg.
Everything in order: the female side of the story suppressed, misunderstood, or condemned" (p.
Accordingly, the statements, including the station house confession derived from the officer's exchange with the suspect, should be suppressed because Miranda warnings had not been provided during the initial exchange at the house.
Doctors Mark Dybul and Tony Fauci were excited by their data on antiretrovirals taken seven days on followed by seven days off, in patients whose virus was very well suppressed when they started.
Researchers believe many of them had been suppressed by Victorian scholars to build a one-dimensional picture of the great admiral.
When symptoms are suppressed by conventional drug therapy, a true cure becomes less likely.
Richard Dutton reexamines the case of A Game at Chess, famously licensed for performance and then suppressed after nine days.
Recently, a strategy of proactively alternating regimens while HIV is suppressed has been explored.