syncytiotrophoblast


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syncytiotrophoblast

[sin¦sish·ē·ō′träf·ə‚blast]
(cell and molecular biology)
An irregular sheet or net of deeply staining cytoplasm in which nuclei are irregularly scattered. Also known as plasmoditrophoblast; syncytial trophoblast.
References in periodicals archive ?
The syncytiotrophoblast of placenta serves as an endocrine gland.
This is thought to be a potent stimulus for the activation of Xanthine Oxidase, which is an important source for generation of superoxide free radicals and this takes place in abundance in cytotrophoblast, syncytiotrophoblast and villous stromal cells.
sup][5] It is localized to the maternal-facing apical membrane of placental syncytiotrophoblast and possesses the capacity to actively extrude a wide range of drugs back to the maternal circulation.
Furthermore, in situ hybridization and immunohistochemistry of placental tissue showed that placental LEP in humans is expressed in syncytiotrophoblast cells (facing maternal circulation) and villous vascular endothelial cells (facing fetal circulation) (Lea et al.
Villous immaturity, edema, hypervascularity, stromal fibrosis and calcification, focal syncytiotrophoblast necrosis, and mild lymphocytic deciduitis may also be present (Figure 6, A through C).
He added that 15 years ago, it first became clear that placental parasite infestation was the result of adhesion of chondroitin sulfate proteoglycan (CSPG) to the syncytiotrophoblast cell surface, and that the P.
In pregnancy PAI-1 is also secreted by the syncytiotrophoblast, where its increased mRNA levels have been histologically determined in preeclamptic placentas with IUGR [17].
43) As it exhibits a high level of expression in syncytiotrophoblast cells in the human placenta, it was proposed that syncytin is essential for formation of these cells.
Periodic acid Schiff reaction positive and basophilic granulosity in the syncytiotrophoblast is weak.
The primary change was a deterioration of cytochrome c oxidase in the villous syncytiotrophoblast, which consequently resulted in a lack of energy supply and placental insufficiency.
falciparum erythrocyte membrane protein 1 variant that binds to chondroitin sulfate A (CSA) on the syncytiotrophoblast (11,12).