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Related to synergistic: synergistic muscles, Synergistic effect


A muscle that assists a prime mover muscle in performing a specific action.
A material that enhances the effect of another material so that when they are combined the total effect is greater than the sum of their individual effects.



(1) In anatomy and physiology, a muscle (or group of muscles) that acts jointly and functions homogeneously with another muscle (or group of muscles) in the same movement.

Examples of synergists in mammals (including humans) are the external intercostal and intercartilagtnous muscles and the muscles of the diaphragm, which, by contracting simultaneously, ensure the act of inhalation. Muscles that act together in performing a particular movement may be antagonists in the execution of other movements. The phenomenon of synergism is ensured by the regulatory activity of the central nervous system.

(2) In pharmacology, one of several medicinal agents used jointly whose combined effect on the body exceeds the effect exerted by each separately. Direct synergists act on the same reactive systems of the body, such as the simultaneous influence of two adrenomimetic substances. Indirect synergists exert the same end effect but differ in their mechanisms of action. For example, adrenaline and atropine act along different pathways to produce dilatation of the pupils; when taken together, the overall effect of these substances on the pupil exceeds the effect of each separately.

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The combination of ampicillin and cefixime showed as synergistic for a single isolate of E.coli.
In conclusion, our preliminary investigation showed that the aqueous extracts of date palm and almond exhibited synergistic antimicrobial activity with amoxicillin against Gram negative pathogens P.
The growth inhibitory effect of Icariside II alone was moderate at 10 [micro]g/ml, but significant synergistic activities against RAW264.7 cell growth were observed when combinations of 10 [micro]g/ml Icariside II with 10 [micro]g/ml EHE (Fig.
In order for a CRO to function in a synergistic manner, it is important that the biotech company share proprietary information, in a legally protected way, of course, with the CRO.
Table 2: Synergistic effects of the cryptotanshinone with oxacillin in isolated MRSA, VRSA, MSSA, and some of reference bacteria.
Mosambee is an mPOS product developed by Synergistic Financial Networks, India and is being launched in the UAE and other parts of Asia with active support from Visa and will soon expand to other regions.
The maximum synergistic effect was achieved using a PEF treatment of 10 kV per cm for 3000 [micro]s on skim milk that had been supplemented with cinnamon at 5% levels.
Synergistic Technology Solutions, 847-968-5501,
Harry Macklowe, chairman of Macklowe Properties said the properties provided a "synergistic compliment" to his existing portfolio and the purchase was consistent with his long term objectives.
National Cancer Institute (NCI), the combination of REOLYSIN(R) and paclitaxel was uniformly synergistic against six non-small cell lung cancer cell lines examined, including cell lines resistant to paclitaxel or REOLYSIN(R).
The book also explores the evolving political economy of children's films, as these movies were integrated into synergistic marketing strategies involving toy manufacturers and fast food restaurants.
Significant effort has been devoted to the study of synergistic extractions over the last decades as the very nature of synergism offers interesting possibilities of research into both the chemistry of these extractants and their practical applications.