Synthetase


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Related to Synthetase: Glutamine synthetase

synthetase

[′sin·thə‚tās]
(biochemistry)

Synthetase

 

the common name for an enzyme of the class of ligases. As opposed to synthases, synthetases effect condensation reactions, which are accompanied by the decomposition of energy-rich bonds in nucleoside triphosphates, including ATP.

References in periodicals archive ?
By Sanger sequencing, compound heterozygous mutations in alanyl-transfer RNA (tRNA) synthetase 2 ( AARS2 ) (OMIM*612035) were detected [Figure 1]g.
In normal liver, glutamine synthetase (GS) expression is restricted to centrilobular (zone 3) hepatocytes, (125) positive in only one to a few hepatic plates around central veins (Figure 6, A, inset).
The reason that intralesional TCA alone is less effective than combination therapy with intralesional TCA and 5-FU is that in addition to inhibitory effect on TGF-ss-induced expression of type 1 collagen gene in human fibroblasts, 5-FU has an inhibitory effect on production of thymidylate synthetase, thus blocking DNA synthesis.
Koblin DD, Watson JE, Deady JE, Stokstad ELR, Eger EIL Nitrous oxide inactivates methionine synthetase in human liver.
Keywords: Spring wheat; Nitrogen fertilizers; Glutamine synthetase enzyme; Yield capacity; Photosynthetic potential; Photosynthesis net productivity
Isolation and purification of recombinant plasmid DNA from transformed cells: Agrobacterium tumefaciens strain LBA4404, harbouring the binary vector pBI121, containing the P5CS gene which encodes D1-pyrroline-5-carboxylate synthetase (P5CS) and the bar gene (bialophos herbicide resistant gene) as a selectable marker under the control of the cauliflower mosaic virus 35S promoter (P35S) and NOS terminator were used for transforming grape explants (Fig.
com)-- A team of researchers from Portugal have discovered that genetic changes in the gene oligodenylate synthetase 1 (OAS1) could be associated with the aggressiveness of tumours in breast and prostate cancer.
Acyl-CoA Synthetase and Acetyl-CoA Synthetase are enzymes present in the fatty acid metabolism, preserved in D.
Iron acts as a coenzyme for Nitric Oxide Synthetase (NOS), which synthesize Nitric Oxide (NO) and that is important for maintenance of basal gallbladder tone and normal relaxation.
The addition of interleukin 13 and TNF-Alpha resulted in increased expression of nitric oxide synthetase in these groups.
The nine target genes were acyl-CoA synthetase long-chain family member 6 (ACSL6), apolipoprotein A-I (APOA1), PLTP, GK, CPT2, aquaporin 7 (AQP7), acyl-Coenzyme A oxidase 1 palmitoyl (ACOX1), ACOX2, and FABP4.