synthetic chromosome

synthetic chromosome

[sin¦thed·ik ′krō·mə‚sōm]
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It is the first synthetic chromosome ever assembled based on a eukaryotic organism, which stores DNA in nuclei.
We have shown that yeast cells carrying this synthetic chromosome are remarkably normal," he said.
" This is the first synthetic cell that's been made, and we call it synthetic because the cell is totally derived from a synthetic chromosome, made with four bottles of chemicals on a chemical synthesiser, starting with information in a computer," said Venter.
"We call it synthetic because the cell is totally derived from a synthetic chromosome, made with four bottles of chemicals on a chemical synthesizer, starting with information in a computer." The team has earlier chemically synthesized a bacterial genome, and has also transplanted the genome of one bacterium to another.
American Venter has created a synthetic chromosome from lab chemicals which will be transplanted into a living bacterial cell.
It shows that our synthetic chromosome is hardy, and it endows the yeast with new properties," Boeke added.
So it's a whole new paradigm, the first time we have a cell that is totally controlled 100 per cent by a synthetic chromosome," the Independent quoted him as saying.
Neochromosome designs, builds and optimizes entire synthetic chromosomes that augment a host cell's genetic information, analogous to upgrading a computer's operating system.
Surprisingly, the yeast cells still grew normally even though the synthetic chromosomes were not exact copies of their natural counterparts.
The Gene-BrickTM premier gene synthesis service is specifically designed to meet demands of large DNA fragments which are used in synthetic biology research, such as the building of large genetic circuits and synthetic chromosomes.