systemic circulation


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Related to systemic circulation: Coronary circulation

systemic circulation

[si′stem·ik ‚sər·kyə′lā·shən]
(physiology)
The general circulation, as distinct from the pulmonary circulation.
References in periodicals archive ?
###semination into the systemic circulation of elevated numbers of neutrophils, as well as LPS and IL-6 may
SCFAs are absorbed into the systemic circulation and cross the blood-brain barrier.
Given the exceptional sensitivity of the high-sensitivity troponin assays, we hypothesized that we would detect longer cTnI and cTnT polypeptides in the systemic circulation. This hypothesis was supported by the fact that both of the high-sensitivity assays for cTnT and cTnI were substantially more sensitive to cTn in cooked ovine than in human myocardium.
However, efficacy in the fellow eye should be expected to derive from the systemic circulation.
Portal venous flow and velocity are reduced in patients with cirrhosis and large SRS, compared with normal subjects and patients with chronic hepatitis [14] due to the venous blood shunting in the systemic circulation which determines an increase of cardiac output.
Moreover, sodium laurate goes into systemic circulation and destroys the integrity of vascular walls, followed by serious and progressive in situ thrombosis and organ dysfunction.
Defined as a failure of normal circulatory transition at birth, or more specifically as failure of the pulmonary vasculature to relax after birth, with continued shunting of non-oxygenated blood into the systemic circulation via fetal channels (ductus arteriosus and foramen ovale), it remains a challenging neonatal emergency to manage.
The extrahepatic route bypasses the portal sinus, such that an abnormal venous channel connects the umbilical vein directly to the systemic circulation. This channel may join the right atrium, IVC, renal vein, iliac veins or, less commonly, the left atrium and coronary sinus.
* P-glycoprotein acts as a cell membrane pump and increases the elimination of loperamide from the CNS and systemic circulation.
"We chose to measure bioavailability using area under the plasma concentration curve (AUC) because it accurately represents the total amount of unchanged active compounds that reach systemic circulation. The results demonstrate the proven bioavailability of Lutemax 2020 at all three tested doses."
The truncus arteriosus is characterized by the presence of a single arterial vessel emerging from the base of the heart and irrigates the coronary bed, the pulmonary circulation, the systemic circulation, and usually presents interventricular communication.
The concentration of colchicine that enters systemic circulation with ColciGel is less than 50 pg/mL.

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