initiator tRNA

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initiator tRNA

[i¦nish·ē‚ād·ər ¦tē‚är‚en′ā]
(cell molecular)
A special type of transfer ribonucleic acid (RNA) that initiates protein synthesis by binding to the amino acid methionine and delivering it to the small ribosomal subunit.
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References in periodicals archive ?
The lengths of the two mitogenome are 16,546 bp and 16,545 bp, which both consist of 13 typical vertebrate protein-coding genes, 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes and one putative control region.
Most metazoan mitochondria have 22 tRNA genes, including two copies of trnL (recognizing the codons UUR and CUN) and two copies of trnS (recognizing AGN and UCN); all the other amino acids are handled by one tRNA species each (Podsiadlowski et al.
The study serendipitously found evidence for another proposal about tRNAs. Each modern tRNA has at its lower end an "anticodon" that it uses to recognize and stick to a complementary codon on an mRNA.
For instance, Rando investigates a category of the molecules known as transfer RNAs (tRNAs).
Yi et al., "The tRNA methyltransferase NSun2 stabilizes [p16.sup.INK4] mRNA by methylating the 3' -untranslated region of p16," Nature Communications, vol.
Besides, steady state tRNA levels performed with northern blot in the patient's skeletal muscle revealed 95% reduction of the tRNATyr amount in total skeletal muscle RNA [7].
Pathogenic variants in the glycyl tRNA synthetase (GARS) gene have been described in association with a specific form of an autosomal dominant motor axonal neuropathy that preferentially involves the upper limbs known as distal hereditary motor neuropathy V (dHMN-V) or spinal muscular atrophy type Va (dSMA-Va).
Speaking of RNA-[Mn.sup.2+] interaction, we could observe a selective and progressive broadening of NMR signal lines in the [sup.1]H NMR spectrum of tRNA in the region of 5-8 ppm where the proton signals of nitrogenous bases are located (Figure 2(d)).
coli 70S ribosome complex with tRNA and elongation factor G (EF-G) [36], after a variance map indicated some highly variable regions.
Berkhout, "A miRNA-tRNA mix-up: tRNA origin of proposed miRNA," RNA Biology, vol.
Panel B of Table 1 summarizes the results for the sample with TRNA data that I use in this study.
Finally, the news data are available from the Thompson-Reuters News Analytics (TRNA) dataset for the period April 1996 through December 2012.