Angiotensin II-induced tachyphylaxis
in aortas of normo- and hypertensive rats: changes in receptor affinity.
As nonprandial GLP-1 receptor agonists have longer half-lives and prolonged action, the gastric emptying effect is reduced by tachyphylaxis
and their influence on postprandial glycemia is thus diminished by comparison with prandial agonists [81-84].
after intravitreal bevacizumab for exudative age-related macular degeneration," Retina, vol.
The first response to octreotide administration is usually hyperglycaemia followed by a blunted effect after 48 hours (tachyphylaxis
We think that this course was not associated with tachyphylaxis
but might be related with starting therapy with a more aggressive disease and insurance issues because we could not perform regular DEX implants.
TAS2R activation promotes airway smooth muscle relaxation despite [beta] (2)-adrenergic receptor tachyphylaxis
In parallel, the innate repertoire (adhesion molecules, PRRs, innate receptors, etc.) is continuously changing through the degree of expression, tachyphylaxis
, due to secondary molecular modifications (changes in glycosylation, glycation), and so forth, thus affecting the strength/quality of interactions and integrated signaling.
Over time, treatment becomes less effective, with treatment failure due to tachyphylaxis
occurring after a few days.
"Top-up" doses of 50 to 100 mcg (up to 1000 mcg daily) of sc octreotide can be used when symptoms are not adequately controlled with the long acting SS-analogs or in the unusual event of tachyphylaxis
. Recent studies have also demonstrated that symptomatic control may also be obtained by either increasing the frequency (every two or three weeks) or the dose of long acting SS-analog administration; doses as high as 120mg/month of octreotide LAR have been used without major toxicity [29-32].
One child woke up during surgery (ketamine tachyphylaxis
) and 6 children had delayed anaesthetic reversal.
(8) The incidence of adverse events related to study drug decreased over the course of the study, and no tachyphylaxis