tachyphylaxis


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tachyphylaxis

[‚tak·ə·fə′lak·səs]
(immunology)
Rapid desensitization against doses of organ extracts or serum by the previous inoculation of small subtoxic doses of the same preparation.
References in periodicals archive ?
Targum, "Identification and treatment of antidepressant tachyphylaxis," Innovations in Clinical Neuroscience, vol.
Patients treated with DR-prednisone maintained their morning stiffness responses with no evidence of tachyphylaxis for up to 1 year.
In general, in the early period, infection, nerve damage, hemorrhage, seroma, intervention area pain, electrode migration, negative impact on bowel movements, long-term body reaction to the system, development of wounds in the skin owing to erosion, removal of the battery and connections, infection, problems regarding battery or electrode, programming problems, and tachyphylaxis development might be observed.
Tachyphylaxis can develop within 6 weeks of medication use, limiting long-term efficacy.
Stopping the medication did cause a kind of tachyphylaxis seen with other alpha-adrenergics used to treat nasal or conjunctival congestion, where stopping the drug increased erythema or edema.
Once-weekly dosing might lessen the risk of side effects or tachyphylaxis, she noted.
ephedrine has been recommended in this role, but its position has been challenged because of potential complications that include supraventricular tachycardia, tachyphylaxis and fetal acidosis [2,3].
Tachyphylaxis, or a rebound effect, sometimes occurs with the use of other decongestants as well, such as nasal sprays.
The study suggested that sildenafil did not act through nitric oxide (NO) or cyclic guanosine monophosphate (cGMP) pathways and, so, tachyphylaxis to the chronic effect could not be a matter of concern.