Idiopathic juxtafoveolar retinal telangiectasis
. Update of classification and follow-up study.
Clinical features of idiopathic juxtafoveal telangiectasis
Early stages of Coats' disease involve telangiectasis
in the temporal macula and mid-periphery.
Stage Histopathologic alterations in the gills I Hypertrophy and hyperplasia of gill epithelium Sanguineous congestion Dilation of marginal vascular channels Lifting of respiratory epithelium Fusion and disorganisation of secondary gill lamellae Shortening of secondary lamellae Leukocyte infiltration of gill epithelium Aggregation of cells of the primary lamella II Haemorrhage and rupture of lamellar epithelium Hypertrophy and hyperplasia of mucous cells Empty mucous cells or their disappearance Hypertrophy and hyperplasia of chloride cells III Lamellar aneurism Necrosis and cell degeneration Lamellar telangiectasis
Vascular hamartomas are classified as capillary telangiectasis
, cavernous angiomas, and arteriovenous or venous malformations.
The histopathological differential diagnoses are hereditary hemorrhagic telangiectasis
, Schistosomiasis, alcoholic liver disease and fibrosis due to other causes.
Garretson, "Intravitreal triamcinolone for the treatment of idiopathic juxtafoveal telangiectasis
,' Retina, vol.
It was first described by Gass and Oyakawa  and Gass and Blodi  and named idiopathic juxtafoveolar retinal telangiectasis
Louis showed that daily doses of chloroquine or hydroxychloroquine reduced insulin resistance and improved lipid metabolism, most likely via activation of the ataxia telangiectasis
mutated (ATM) gene (Cell Metab.
noted on secondary lamellae may be due to the dilation of small blood vessels by Cr(VI) toxicity.
(5) Diagnosis is made in the presence of three of the following: recurrent spontaneous epistaxis, mucocutaneous telangiectasis
, an autosomal dominant familial distribution, and visceral AVMs.
Bovine liver telangiectasis
, a focal dilation and congestion of a group of hepatic sinusoids, is the most common liver lesion in cattle from different countries of the world [3,5,11,16,20,23,24,28].