teratogen


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teratogen

[tə′rad·ə·jən]
(medicine)
An agent causing formation of a congenital anomaly or monstrosity.
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References in periodicals archive ?
Factors implicated in the etiology are genetics, compromised vasculature of the skin, infection, teratogens, fetus papyraceus and trauma.
This is why it was important to develop a model encompassing both cell differentiation and migration that would give researechers a more complete and accurate picture of the effects of teratogens on the developing embryo.
Furthermore, the bioactive teratogenic compounds present can also be develop into an anticancer drugs since almost anticancer drugs are teratogens in nature.
An analysis of exposure to potential teratogens showed that 1.5% (9/591) of the mothers, for whom this information was available, were on antiepileptic therapy at the time of conception, and 0.5% (3/591) of the women had taken traditional medications early in their pregnancies.
Ethanol (alcohol) is an important human teratogen. IT is estimated to affect severely 1.1/1000 live births and have lesser effects in 3-4/1000 children born.
Culturing of whole embryos at an early stage of organogenesis, and exposing of these to a potential teratogen, allows for the valuation of a relative index of teratogenicity of the test substance (2).
Many of these children display a range of cognitive and behavioural disorders (Welch-Carre 2005), which has led to alcohol being regarded as a behavioural teratogen and a leading cause of mental retardation in the Western world (Dunty 2001).
Meclizine has been a "suspect" teratogen for years, as indicated by Schardein (1993).
Researchers also note that since it is a relatively weak teratogen compared to other pesticides, it is used more often in the home, without specific consideration of whether pregnant women or young children are present.
If studies of larger populations confirmed their findings that ethanol (rather than other substances in alcoholic beverages) was a teratogen, by what means did it act?
Kenneth Lyons Jones of the University of California, San Diego and his colleagues studied 228 pregnant women who called the California Teratogen Information Service (CTIS) from 1989 through 1995 because they were taking fluoxetine.
REPRORISK now includes TERIS Teratogen Information System, Shepard's Catalog of Teratogen Agents, The REPROTOX database and REPROTEXT Reproductive Hazard Reference.