teratogen

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teratogen

[tə′rad·ə·jən]
(medicine)
An agent causing formation of a congenital anomaly or monstrosity.
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The lesion described in our case 1 comes under group 8 of Frieden classification which occurs after teratogen exposure.
Clearly, there is a gap between current and optimal practice when teratogens are prescribed to women of reproductive age.
Due to this geometric restriction, it was possible for the researchers to study the effect of teratogens, which may alter the shape and even the eventual position of the mesoendoderm layer.
11,28] Several theories have been postulated to explain these observations and include the suggestion that the process of neurulation may occur at slightly different times in the development of male and female embryos, thereby accounting for differing susceptibilities to the effects of factors such as teratogens.
Numerous studies have substantiated the association between teratogens and clefting.
Studies comparing chemicals drawn from a variety of classes suggest that the percentage of teratogens detected may vary between 60 and 90%, and the percentage of non-teratogens detected may vary between 89 and 100% depending on the test configuration selected, the choice of compounds and the length of exposure to test agent (12-14).
Teratogens differ from mutagens in that they generally do not damage genes or chromosomes (Jones 2006).
Beta 2 adrenergic agonist drugs are widely used in obstetrics as tocolytics to inhibit or slow down labour and bronchodilators, but may act as functional and behavioural teratogens when given continuously in the mid to late second or early third trimesters.
Some teratogens such as drugs and alcohol are well documented, but others may be exerting their harmful effect without knowledge from the mother.
His mother had not been exposed to medicines or teratogens during her pregnancy.
These are potential human teratogens, although the absolute risk they pose is small.