Among the cases, abnormal terminal bronchioles
and pulmonary vessels showing features of peribronchiolitis and perivasculitis appeared as thickening in the wall of terminal bronchiole
and in the wall of pulmonary vessels due to lymphocytic infiltration (Figure-4).
may become ectatic as the disease advances.
In rats, which lack respiratory bronchioles, lymphatic vessels are located adjacent to the terminal bronchioles
, but not at the alveolar level.
The major site of impact and injury appeared to be the terminal bronchiole
and adjacent first-generation respiratory bronchioles, with progressive decrease in both retention of particles and injury in the second- and third-generation respiratory bronchioles.
According to ELHAFEZ (2012), the canalicular stage is an important step in the development of the rabbit lung, since the terminal bronchioles
branches into 2-4 acinar channels, from which some cells of the epithelium line these channels and differentiate into type I pneumocytes.
3] Histologically, CCAM are benign hamartomatous or dysplastic lung tumor, showing adenomatous overgrowth of terminal bronchioles
with reduction in alveoli.
The inflammatory response associated with MWCNT exposure was characterized by neutrophilia as determined by BALF cell differentials (Figure 4B) and by using immunohistochemical staining with an anti-neutrophil antibody, which revealed neutrophils near terminal bronchioles
and in proximity to macrophages containing O-MWCNTs (Figure 4C).
Congenital cystic adenomatoid malformation is an embrionic developmental disorder characterized by cystic enlargement and overgrowth of terminal bronchioles
which are surrounded by various epithelial cells.
The researchers also used microCT to measure the number and cross-sectional area of the small terminal bronchioles
, and performed histologic analysis to count the number of small airways per square centimeter and to measure the thickness of airway walls.
carcinogenesis) or some forms of developmental damage to the fetus (More serious inflammation: more toxic agents and/or higher exposures may be associated with damage resulting in inflammation for example of terminal bronchioles
and alveoli leading to a chemical pneumonitis and pulmonary oedema (e.
the terminal bronchioles
, alveolar ducts, and alveolar sacs.