testicular feminization


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Related to testicular feminization: Complete Androgen Insensitivity Syndrome

testicular feminization

[tes¦tik·yə·lər ‚fem·ə·nə′zā·shən]
(medicine)
A hereditary disorder in which affected individuals are chromosomally XY but have a feminine phenotype and are sterile. The X-linked testicular feminization (Tfm) gene results in absent or defective testosterone receptors, leaving cells unable to bind androgens and respond even though normal male levels of androgen are present. Also known as androgen insensitivity syndrome.
References in periodicals archive ?
The surgical management of incomplete testicular feminization in three sisters.
INTRODUCTION: Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal woman with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair.
Inguinal hernia in females and testicular feminization syndrome.